Induced pluripotent stem (iPS) cells have attracted enormous attention due to their vast
potential in regenerative medicine, pharmaceutical screening and basic research. Most prior …

Recently induced pluripotent stem (iPS) cells are derived from somatic cells by ectopic
expression of several transcription factors (reprogramming factors) using technology of …

The introduction of four transcription factors Oct4, Klf4, Sox2 and c-Myc by viral transduction
can induce reprogramming of somatic cells into induced pluripotent stem cells (iPSCs), but …

Induced pluripotent stem cell (iPSC) technology that could revert the fate of terminally
differentiated somatic cells into embryonic stem cell–like status by using ectopic expression …

Induced pluripotent stem cells (iPSC s) are considered patient‐specific counterparts of
embryonic stem cells as they originate from somatic cells after forced expression of …

Conversion of cell fate is not only an essential biological question, but also has great clinical
values. In early 1950s, cellular reprogramming was first achieved using the technique of …

Importance of the field: The generation of induced pluripotent stem cells (iPSCs) enabled by
exogenous expression of the canonical Oct4, Sox2, Klf4 and c-Myc reprogramming factors …

The discovery of induced pluripotent stem (iPS) cells provides not only new approaches for
cell replacement therapy, but also new ways for drug screening. However, the undefined …

The detailed mechanism of reprogramming somatic cells into induced pluripotent stem cells
(iPSCs) remains largely unknown. Partially reprogrammed iPSCs are informative and useful …

Induced pluripotent stem cells (iPSCs) were originally derived from adult somatic cells by
ectopic expression of the stem cell transcription factors OCT3/4, SOX2, c-Myc, and KLF4 …