Sepsis is currently the main factor of death in the ICU, and the liver, as an important organ of
immunity and stable metabolism, can be acutely damaged during sepsis, and the mortality …

Sepsis, a life-threatening syndrome with uncontrolled inflammatory response, causes high
morbidity and mortality worldwide. Currently, satisfactory treatments on sepsis are still …

Abstract Background Huanglian Jiedu Decoction (HLJDD) is a classical herbal formula with
potential efficacy in the treatment of sepsis. However, the main components and potential …

Objective: This work aims to explore the potential targets and underlying therapeutic
mechanisms of celastrol in autoimmune hepatitis (AIH) through network pharmacology and …

Sesamin has been described to exert anti-oxidant and anti-inflammatory properties. In
present study, we investigated the potential effects and mechanisms of sesamin on …

Abstract Background & Aims Silibinin-phospholipid complex (SPC) has been utilized to treat
acute liver injury clinically. Nevertheless, the hepatoprotective mechanism of SPC remains …

Eclipta, a traditional Chinese medicine, has been used to treat liver disease for centuries.
However, the chemical basis and biological mechanisms of Eclipta remain elusive. The …

The present study was designed to target fish for potential bioactive components contained
in a Huang Lian Jie Du decoction (HLJDD) and identify the underlying mechanisms of action …

Puerarin, an isoflavone component extracted from herb radix puerariae, is widely used in
China in the treatment of immune diseases and inflammation. Previous studies have …

Acute liver injury (ALI) refers to the damage to the liver cells of patients due to drugs, food,
and diseases. In this work, we used a network pharmacology approach to analyze the …