Research question: Does hyperandrogenism affect ovarian granulosa cells (GCs) function
through activation of ferroptosis? Is hyperandrogen-induced ferroptosis regulated by …

STUDY QUESTION Does ovarian ferroptosis play an active role in the development of
polycystic ovary syndrome (PCOS)? SUMMARY ANSWER Increased ovarian ferroptosis …

Ferroptosis, a form of regulated cell death, was first defined in 2012. Ferroptosis mainly
involves iron-driven lipid peroxidation damage of cells. This process is regulated by iron …

Ferroptosis, an iron-dependent type of regulated cell death, is triggered by the accumulation
of lethal lipid peroxides. Due to its potential in exploring disease progression and highly …

Polycystic ovarian syndrome (PCOS) is a common heterogeneous reproductive endocrine
metabolic disorder in women of reproductive age characterized by clinical and biochemical …

Ferroptosis is widely present in fibrosis-related diseases. The basic pathology of premature
ovarian insufficiency (POI) involves ovarian tissue fibrosis, and there are currently fewer …

Ferroptosis is a novel type of programmed cell death dependent on iron and characterized
by the accumulation of lipid peroxides in cells and is closely related to various diseases …

Study question Does trophoblasts of PCOS patients with aberrant iron metabolism, and how
does metformin ameliorate androgen-induced ferroptosis in trophoblasts in vivo and in vitro …

Iron, as an essential trace element for the organism, is vital for maintaining the organism's
health. Excessive iron can promote reactive oxygen species (ROS) accumulation, thus …

Ferroptosis is a relatively novel form of regulated cell death that was discovered in 2012.
With the increasing research related to the mechanisms of ferroptosis, previous studies have …