[PDF][PDF] The mechanism of hepatotoxicity of Nux Vomica: a network-pharmacology-based study

A Zhao, J Xu, S Li, R Gong, L Ma, X Li - Toxicol Commun, 2022 - tmrjournals.com
Objective: To explore the potential mechanism of hepatotoxicity induced by Nux Vomica
through network toxicology. Methods: The active components and targets of Nux Vomica …

Molecular mechanism and research progress on pharmacology of traditional Chinese medicine in liver injury

HY Zhang, HL Wang, GY Zhong, JX Zhu - Pharmaceutical biology, 2018 - Taylor & Francis
Context: Liver disease is a common threat to human health, caused by a variety of factors
that damage the liver. Recent studies have shown that active ingredients (for example …

Retracted Article: The PI3K/Akt and NF-κB signaling pathways are involved in the protective effects of Lithocarpus polystachyus (sweet tea) on APAP-induced …

J Yang, W Hao, X Liu, Q Shen, Y Li, S Ren, Z Wang… - RSC …, 2020 - pubs.rsc.org
Acetaminophen (APAP)-induced acute liver injury (ALI) is a health issue that has gradually
attracted attention, and is often regarded as a model of drug-induced hepatotoxicity. The …

Exploring the anti-inflammatory and immunomodulatory potential of licochalcone B against psoralidin-induced liver injury

Y Wu, K Feng, Y Chen, H Zhang, M Zhang… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Herb-induced liver injury (HILI) represents an exacerbated
inflammatory response, with Psoraleae fructus (PF) and its preparations recently associated …

Traditional Mongolian medicine (HHQG) attenuates CCl4-induced acute liver injury through inhibiting monocyte/macrophage infiltration via the p-P38/p-JNK pathway

L Wang, Y Bao, H Tong, K Zhang, Y Cheng… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Honghua Qinggan 13 Flavor Pills (HHQG), whose
Mongolian name is Guri Gumu-13, is a traditional Mongolian medicine, that was stated in the …

Study of Xuanhuang Pill in protecting against alcohol liver disease using ultra-performance liquid chromatography/time-of-flight mass spectrometry and network …

X Cui, M Du, K Wei, C Dai, RYH Yang… - Frontiers in …, 2023 - frontiersin.org
Introduction Xuanhuang Pill (XHP) is a traditional Chinese medicine oral formula composed
of 10 herbs. This study aims to verify the hepatoprotective activity of XHP and explain its …

Network pharmacology‐based strategy for predicting therapy targets of traditional Chinese medicine Xihuang pill on liver cancer

X Zhao, J Hao, S Chen - Evidence‐Based Complementary and …, 2020 - Wiley Online Library
Objective. To investigate the potential therapy targets and pharmacological mechanism of
traditional Chinese medicine (TCM) Xihuang pill in liver cancer based on network …

Molecular mechanisms involved in oxidative stress-associated liver injury induced by Chinese herbal medicine: An experimental evidence-based literature review and …

C Zhang, N Wang, Y Xu, HY Tan, S Li… - International journal of …, 2018 - mdpi.com
Oxidative stress, defined as a disequilibrium between pro-oxidants and antioxidants, can
result in histopathological lesions with a broad spectrum, ranging from asymptomatic …

Mechanism of Erzhiwan on hepatocellular carcinoma based on network pharmacology

Z CHEN, Y CHEN, Z MAI, Z YANG… - Chinese Journal of …, 2020 - pesquisa.bvsalud.org
Objective: To explore the possible mechanisms of Erzhiwan in the treatment of
hepatocellular carcinoma (HCC) based on the network pharmacology. Method: The …

Integrating Network Pharmacology and Bioinformatics to Explore the Effects of Dangshen (Codonopsis pilosula) Against Hepatocellular Carcinoma: Validation Based …

Y Yu, S Ding, X Xu, D Yan, Y Fan, B Ruan… - Drug Design …, 2023 - Taylor & Francis
Purpose This study aimed to explore the pharmacological mechanism of Dangshen
(Codonopsis pilosula) against hepatocellular carcinoma (HCC) based on network …