Chemical modification and biological activity exploration of the natural product-gossypol

J Yin - 2010 - tigerprints.clemson.edu
Gossypol is a naturally occurring, highly colored yellow pigment indigenous to the small
intercellular pigment glands of the cotton plant genus Gossypium, which is proposed to be …

Structure, properties of gossypol and its derivatives—from physiological activities to drug discovery and drug design

Y Liu, L Wang, L Zhao, Y Zhang - Natural product reports, 2022 - pubs.rsc.org
Covering up to 2022 Gossypol is a polyphenolic compound isolated from cottonseed. There
are two optical enantiomers of gossypol,(−)-gossypol and (+)-gossypol. Gossypol exists as …

Novel O-glycosidic gossypol isomers and their bioactivities

J Yin, L Jin, F Chen, X Wang, A Kitaygorodskiy… - Carbohydrate …, 2011 - Elsevier
Novel glycosidic gossypol analogs, 7, 7′-gossypol diglucoside tetraacetate GS1, 6, 7′-
gossypol diglucoside tetraacetate GS2, 7, 7′-gossypol diglycoside GS1′, 6, 7′-gossypol …

Gossypol-a polyphenolic compound from cotton plant

X Wang, CP Howell, F Chen, J Yin, Y Jiang - Advances in food and nutrition …, 2009 - Elsevier
Abstract Gossypol (C 30 H 30 O 8) is a polyphenolic compound derived from the cotton plant
(genus Gossypium, family Malvaceae). The presence of six phenolic hydroxyl groups and …

Unexpected formation of N-methylfulleropyrrolidines by the reaction of fullerene and gossypol and their bioactivity

J Yin, M Nigh, D Vanderveer, Y Jiang, X Wang, F Chen - Carbon, 2009 - Elsevier
Reaction of fullerene, sarcosine and gossypol through the Prato reaction resulted in some
unexpected N-methylfulleropyrrolidines. These fulleropyrrolidines were fully characterized …

Reaction chemistry of gossypol and its derivatives

JA Kenar - Journal of the American Oil Chemists' Society, 2006 - Wiley Online Library
Gossypol, a complex polyphenolic compound, is a naturally occurring highly colored yellow
pigment found in the small intercellular pigment glands in the leaves, stems, roots, and seed …

Recent advances in gossypol derivatives and analogs: a chemistry and biology view

Y Lu, J Li, CE Dong, J Huang, HB Zhou… - Future Medicinal …, 2017 - Taylor & Francis
Gossypol as a natural occurring polyphenol has been studied in a wide range of therapeutic
contexts for a long time. The chemical modifications on gossypol were limited due to the …

New function of gossypol, a natural product of cotton

J Huang, X Chen - Journal of Cotton Research, 2022 - Springer
Cotton plants are not only the global crops integrating fiber, oil and protein (Hu et al. 2020;
Xiao et al. 2017), but also the medicinal plants with potent application values, which were …

Gossypol and its natural derivatives: multitargeted phytochemicals as potential drug candidates for oncologic diseases

D Pal, P Sahu, G Sethi, CE Wallace, A Bishayee - Pharmaceutics, 2022 - mdpi.com
Despite the vast amounts of research and remarkable discoveries that have been made in
recent decades, cancer remains a leading cause of death and a major public health concern …

Gossypol

BT Ibragimov, SA Talipov - Encyclopedia of Supramolecular …, 2013 - api.taylorfrancis.com
Gossypol (Gp) is a natural polyphenolic compound [1] found in different organs of the cotton
plant. This yellow pigment exists in plants as a protective agent against insects and diseases …