Progress in the diagnosis of leishmaniases depends on the development of effective
methods and the discovery of suitable biomarkers. We propose firstly an update …

Zoonotic cutaneous leishmaniasis caused by Leishmania (L.) major parasites affects urban
and suburban areas in the center and south of Tunisia where the disease is endemo …

Polymorphic DNA sequences have been amplified using different PCR-based techniques
and used for species identification, strain discrimination and population genetic studies in …

Leishmaniases remain a major public health problem. Despite the development of elaborate
experimental techniques and sophisticated statistical tools, how these parasites evolve …

Background The current disease model for leishmaniasis suggests that only a proportion of
infected individuals develop clinical disease, while others are asymptomatically infected due …

Leishmania are digenetic protozoa which inhabit two highly specific hosts, the sandfly where
they grow as motile, flagellated promastigotes in the gut, and the mammalian macrophage …

Evidence is provided for genetic and biological variation among Leishmania major strains
that correlates with their geographical origin. The host–parasite relationship also appears to …

Visceral leishmaniasis (VL), the most severe form of leishmaniasis, is caused by Leishmania
donovani. In addition to fatal VL, these parasites also cause skin diseases in immune …

Symptoms of human leishmaniasis range from subclinical to extensive systemic disease
with splenomegaly, hepatomegaly, skin lesions, anemia and hyperglobulinemia, but the …

The precise identification of the parasite species causing leishmaniasis is essential for
selecting proper treatment modality. The present study aims to compare the nucleotide …