Common variants in the HLA-DRB1HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis

LeishGEN Consortium… - Nature …, 2013 - nature.com
To identify susceptibility loci for visceral leishmaniasis, we undertook genome-wide
association studies in two populations: 989 cases and 1,089 controls from India and 357 …

Amplified fragment length polymorphism (AFLP) analysis is useful for distinguishing Leishmania species of visceral and cutaneous forms

A Kumar, VR Boggula, P Misra, S Sundar, AK Shasany… - Acta tropica, 2010 - Elsevier
The Leishmania strains belonging to cutaneous leishmaniasis (CL) and visceral
leishmaniasis (VL) have been reported to possess close homology in genome profiles. To …

Mapping the Genes for Susceptibility and Response to Leishmania tropica in Mouse

Y Sohrabi, H Havelková, T Kobets, M Šíma… - PLoS neglected …, 2013 - journals.plos.org
Background L. tropica can cause both cutaneous and visceral leishmaniasis in humans.
Although the L. tropica-induced cutaneous disease has been long known, its potential to …

[HTML][HTML] LSHGD: a database for human leprosy susceptible genes

CGP Doss, N Nagasundaram, J Srajan, C Chiranjib - Genomics, 2012 - Elsevier
Studies aiming to explore the involvement of host genetic factors to determine susceptibility
to develop disease and individual's response to the infection with Mycobacterium leprae …

Evolutionary genetics and molecular diagnosis of Leishmania species

AL Bañuls, M Hide, M Tibayrenc - Transactions of the Royal Society of …, 2002 - Elsevier
An extensive study has been performed on various natural populations of Leishmania from
the 'Old'and 'New Worlds' using multilocus enzyme electrophoresis and random …

Evaluation of cytochrome b sequence to identify Leishmania species and variants: the case of Panama

M Davila, V Pineda, JE Calzada, A Saldaña… - Memórias do Instituto …, 2021 - SciELO Brasil
BACKGROUND The genetic heterogeneity of Leishmania parasites is a major factor
responsible for the wide variety of Leishmania-associated manifestations. Consequently …

A brief introduction to leishmaniasis epidemiology

L Gradoni - The leishmaniases: old neglected tropical diseases, 2018 - Springer
The eco-epidemiological and medical complexity of leishmaniases is a major cause of their
neglect worldwide, despite they represent one of the largest disease burdens among …

[HTML][HTML] Genetic diversity in natural populations of New World Leishmania

E Cupolillo, H Momen, G Grimaldi Jr - Memórias do Instituto Oswaldo …, 1998 - SciELO Brasil
Our results have shown the wide diversity of parasites within New World Leishmania.
Biochemical and molecular characterization of species within the genus has revealed that …

Parasitic genotypes appear to differ in leishmaniasis patients compared with asymptomatic related carriers

M Hide, E Marion, C Pomares, R Fisa, P Marty… - International Journal for …, 2013 - Elsevier
For numerous infectious diseases affecting humans, clinical manifestations range from
asymptomatic forms to severe pathologies. The originality of this study was its focus on …

Microsatellite analysis reveals genetic structure of Leishmania tropica

JM Schwenkenbecher, T Wirth, LF Schnur… - International journal for …, 2006 - Elsevier
The current rapid spread of leishmaniases caused by Leishmania tropica and the complexity
of its clinical spectrum call for this parasite's epidemiological and evolutionary investigation …