Background Cutaneous leishmaniasis (CL) is a major and fast increasing public health
problem, both among the local Pakistani populations and the Afghan refugees in camps …

A genome-wide scan was conducted for visceral leishmaniasis (VL) in Brazil. Initially, 405
markers were typed in 22 multicase pedigrees (28 nuclear families; 174 individuals; 66 …

Different approaches are being developed to improve the differentiation of Leishmania
genus using biochemical and molecular methods. In this study, 11 independent polymorphic …

Abstract Lymphotoxin-α (LT-α) and interleukin-1beta (IL-1β) are proinflammatory cytokines
playing important roles in immunity against Leishmania infection and the outcome of the …

Visceral leishmaniasis (VL) caused by parasites of the Leishmania donovani complex can
be fatal in susceptible individuals. Understanding the interactions between host and …

Approximately 20 Leishmania species are known to cause cutaneous, mucocutaneous, and
visceral disorders in humans. Identification of the causative species in infected individuals is …

A central question in Leishmania research is why most species cause cutaneous infections
but others cause fatal visceral disease. Interestingly, L. donovani causes both visceral and …

We have designed a new genotyping scheme for molecular diagnosis of the different
Leishmania species pathogenic to humans. This scheme is based on PCR amplified …

Three polymerase chain reaction (PCR) assays—kinetoplast DNA (kDNA) PCR, 7SL PCR,
ITS1 PCR—were compared for their ability to detect leishmanial parasites in the skin tissue …

Abstract In the Mediterranean basin, Leishmania infantum is the causative agent of both
visceral and cutaneous leishmaniasis, and is an important opportunistic parasite in patients …