Despite the vast amounts of research and remarkable discoveries that have been made in
recent decades, cancer remains a leading cause of death and a major public health concern …

Gossypol, a polyphenolic aldehyde derived from cottonseed plants, has seen a
transformation in its pharmaceutical application from a male contraceptive to a candidate for …

Gossypol, a natural product extracted from the seed, roots, and stem of cotton, was initially
used as a male contraceptive but was subsequently investigated as a novel antitumor agent …

Gossypol as a natural occurring polyphenol has been studied in a wide range of therapeutic
contexts for a long time. The chemical modifications on gossypol were limited due to the …

Covering up to 2022 Gossypol is a polyphenolic compound isolated from cottonseed. There
are two optical enantiomers of gossypol,(−)-gossypol and (+)-gossypol. Gossypol exists as …

Context: Polyphenols are naturally occurring compounds found in fruits, vegetables, cereals,
and beverages. Polyphenols occupy a unique place in biological science for their …

Plant polyphenol gossypol has anticancer activities. This may increase cottonseed value by
using gossypol as a health intervention agent. It is necessary to understand its molecular …

Abstract Gossypol [(2, 2′-binaphthalene)-8, 8′-dicarboxaldehyde-1, 1′, 6, 6′, 7, 7′-
hexahydroxy-5, 5′-diisopropyl-3, 3′-dimethyl] 1a is a naturally occurring compound …

Gossypol, a male contraceptive drug extracted from cottonseeds, has been found to have
antiproliferative activity on tumour cells and is thought to be a potential anticancer drug. The …

To better use gossypol to find promising anticancer compounds, a series of new and known
bis-Schiff base analogs of chiral gossypol were synthesized, and their anticancer activity on …