Gossypol, a male contraceptive drug extracted from cottonseeds, has been found to have
antiproliferative activity on tumour cells and is thought to be a potential anticancer drug. The …

Gossypol, a male contraceptive drug, has been demonstrated to have antiproliferative and
antimetastatic effects on many kinds of cancer cells in vitro. HT-29 human carcinoma cell …

Gossypol is an attractive therapeutic anti-tumor agent as an apoptosis inducer and is being
evaluated in preclinical tests. However, the molecular mechanisms underlying apoptosis …

Plant polyphenol gossypol has anticancer activities. This may increase cottonseed value by
using gossypol as a health intervention agent. It is necessary to understand its molecular …

Gossypol has wide antineoplastic effects in vitro, but its effects on human lung cancer have
not been explored. 2. To evaluate the activity of gossypol against alveolar cell lung cancer …

Gossypol, a polyphenolic aldehyde derived from cottonseed plants, has seen a
transformation in its pharmaceutical application from a male contraceptive to a candidate for …

Our previous study showed that gossypol (GOS) exhibits potent cytotoxic effects via
apoptosis induction against human colorectal carcinoma cells; however, the role of …

Prostate cancer continues to represent a burgeoning medical problem in the United States.
Recent studies suggest that gossypol, a bioactive phytochemical produced by cotton plants …

Although previous studies demonstrated anticancer activities of gossypol through the
induction of apoptosis, the molecular mechanism (s) responsible for the inhibitory effects of …

Recent studies indicate that gossypol possesses potent antitumor activities in vitro and in
vivo. The nuclear factor-kappa B (NF-κB) plays an important role in tumor cell growth …