Plant polyphenol gossypol has anticancer activities. This may increase cottonseed value by
using gossypol as a health intervention agent. It is necessary to understand its molecular …

Gossypol, a male contraceptive drug extracted from cottonseeds, has been found to have
antiproliferative activity on tumour cells and is thought to be a potential anticancer drug. The …

Metastasis is the most prevalent cause of treatment failure in patients with colon cancer.
Gossypol is reported to exhibit antioxidant, anticancer, antivirus and antimicrobial properties …

Although previous studies demonstrated anticancer activities of gossypol through the
induction of apoptosis, the molecular mechanism (s) responsible for the inhibitory effects of …

Aim: The rapid growth, morbidity and mortality of prostate cancer, and the lack of effective
treatment have attracted great interest of researchers to find novel cancer therapies aiming …

Despite the vast amounts of research and remarkable discoveries that have been made in
recent decades, cancer remains a leading cause of death and a major public health concern …

Compound 1 ((−)-gossypol) has been long known as a chemical anticancer agent. With its
low water solubility and toxicity, it is not widely used as a commercial drug. To overcome …

Gossypol, a natural phenolic aldehyde present in cotton plants, was originally used as a
means of contraception, but is currently being studied for its anti-proliferative and anti …

Recent studies indicate that gossypol possesses potent antitumor activities in vitro and in
vivo. The nuclear factor-kappa B (NF-κB) plays an important role in tumor cell growth …

Gossypol, a polyphenolic aldehyde derived from cottonseed plants, has seen a
transformation in its pharmaceutical application from a male contraceptive to a candidate for …