The “Non-pharmacological treatment of pain” section of the Frontiers in Pain Research was
initiated to reflect the growing appreciation for the role that complementary interventions play …

The future of pain medicine is marked by many questions. What can other nations around
the world learn from the opioid crisis that is still affecting the United States? The American …

Pain is an unpleasant sensation that originates from ongoing or impending tissue damage.
Management of different types of pain (acute, postoperative, inflammatory, neuropathic or …

Neuropathic pain, caused by a lesion or disease affecting the somatosensory system, affects
between 3 and 17% of the general population. The treatment of neuropathic pain is …

Pharmacological approaches to our understanding and treatment of pain have had a long
history and have traditionally relied on very few drugs that either have significant side effects …

Unrelieved pain has major negative effects on the lives of millions of people worldwide, and
is associated with huge societal costs. Breakthroughs in pain therapy have been rare in the …

Objective Persistent pain causes untold misery worldwide and is a leading cause of
disability. Despite its astonishing prevalence, pain is undertreated, at least in part because …

Existing treatments for neuropathic pain deliver inadequate pain relief, unacceptable side
effects, or both. The unmet medical need for more effective treatment is driving a large …

In the general population, the sensation of pain is generally perceived in a negative
connotation because of its association with physical damage to the body and its unpleasant …

Chronic pain afflicts as much as 50% of the population at any given time but our methods to
address pain remain limited, ineffective and addictive. In order to develop new therapies an …