Understanding immunological origins of atopic dermatitis through multi‐omic analysis
R Beheshti, S Halstead, D McKeone… - Pediatric Allergy and …, 2022 - Wiley Online Library
Background The pathophysiology of atopic dermatitis (AD) is multifactorial, impacted by
individual medical, demographic, environmental, and immunologic factors. This study used …
individual medical, demographic, environmental, and immunologic factors. This study used …
Intrinsically defective skin barrier function in children with atopic dermatitis correlates with disease severity
J Gupta, E Grube, MB Ericksen, MD Stevenson… - Journal of Allergy and …, 2008 - Elsevier
BACKGROUND: Recent genetic evidence supports that an underlying defect in skin barrier
function contributes to the pathogenesis of atopic dermatitis (AD). The integrity of the skin …
function contributes to the pathogenesis of atopic dermatitis (AD). The integrity of the skin …
Neuro‐mediators as predictors of paediatric atopic dermatitis
Background Attempts to identify predictors of atopic dermatitis (AD) have focused on genetic
and immunologic factors. However, the role of neuro‐mediators remains to be elucidated …
and immunologic factors. However, the role of neuro‐mediators remains to be elucidated …
A minimally invasive tool to study immune response and skin barrier in children with atopic dermatitis
L Hulshof, DP Hack, QCJ Hasnoe… - British journal of …, 2019 - academic.oup.com
Background Atopic dermatitis (AD) affects children of all skin types. Most research has
focused on light skin types. Studies investigating biomarkers in people with AD with dark …
focused on light skin types. Studies investigating biomarkers in people with AD with dark …
Various diagnostic criteria for atopic dermatitis (AD): A proposal of R eliable E stimation of A topic D ermatitis in C hildhood (REACH) criteria, a novel questionnaire …
SC Lee… - The Journal of …, 2016 - Wiley Online Library
Atopic dermatitis (AD) is a heterogeneous disease that manifests with a wide variety of
clinical symptoms and signs. Due to the lack of definitive biomarkers for AD, it is very difficult …
clinical symptoms and signs. Due to the lack of definitive biomarkers for AD, it is very difficult …
A short period of breastfeeding in infancy, excessive house cleaning, absence of older sibling, and passive smoking are related to more severe atopic dermatitis in …
M Fotopoulou, M Iordanidou, E Vasileiou… - European Journal of …, 2018 - Springer
Background Atopic dermatitis (AD) is one of the most common, chronic or chronically
relapsing inflammatory skin diseases that affect children. Multiple genetic and environmental …
relapsing inflammatory skin diseases that affect children. Multiple genetic and environmental …
[HTML][HTML] Reduced skin microbiome diversity in infancy is associated with increased risk of atopic dermatitis in high-risk children
AS Halling, BG Fritz, T Gerner, MR Rinnov… - Journal of Investigative …, 2023 - Elsevier
It is currently unknown whether alterations in the skin microbiome exist before development
of atopic dermatitis (AD). In this prospective Danish birth cohort of 300 children, we …
of atopic dermatitis (AD). In this prospective Danish birth cohort of 300 children, we …
[HTML][HTML] Introduction of the reliable estimation of atopic dermatitis in childhood: novel, diagnostic criteria for childhood atopic dermatitis
SC Lee, JM Bae, HJ Lee, HJ Kim… - Allergy, Asthma & …, 2016 - synapse.koreamed.org
Purpose Questionnaire-based diagnostic criteria for atopic dermatitis (AD) have been
proposed to detect the major group of AD with flexural dermatitis. We aimed to develop …
proposed to detect the major group of AD with flexural dermatitis. We aimed to develop …
Nasal and skin microbiomes are associated with disease severity in paediatric atopic dermatitis
Background Alterations of the skin microbiome have been associated with atopic dermatitis
(AD) and its severity. The nasal microbiome in relation to AD severity is less well studied …
(AD) and its severity. The nasal microbiome in relation to AD severity is less well studied …
It looks like childhood eczema but is it?
CG Mortz, K Brockow… - Clinical & …, 2019 - Wiley Online Library
In childhood, the most common type of eczema/dermatitis is atopic dermatitis, which occurs
in up to 25% of children world‐wide. However, the diagnosis may sometimes be challenging …
in up to 25% of children world‐wide. However, the diagnosis may sometimes be challenging …