The arteriosclerosis-dependent alteration of brain perfusion is one of the major determinants
in small vessel disease, since small vessels have a pivotal role in the brain's autoregulation …

Small vessel disease (SVD), or microangiopathy, of the cerebral white and central grey
matter is an important subtype of vascular dementia (VD). SVD-dementia is characterised by …

Vascular pathology is the second most common neuropathology of dementia after
Alzheimer's disease (AD), with small vessels disease (SVD) being considered the major …

Subcortical ischemic vascular dementia (SIVD) has been proposed as a subtype of vascular
cognitive impairment. MRI often discloses “silent” hyperintensities in 20% to 40% of …

Vascular cognitive impairment (VCI) is predominately caused by vascular risk factors and
cerebrovascular disease. VCI includes a broad spectrum of cognitive disorders, from mild …

Background Vascular cognitive impairment (VCI) is a heterogeneous entity with multiple
aetiologies, all linked to underlying vascular disease. Among these, VCI related to …

Abstract The World Health Organization reports that 47.5 million people are affected by
dementia worldwide. With aging populations and 7.7 million new cases each year, the …

Cerebral small vessel disease (CSVD) is the most common, chronic and progressive
vascular disease. The changes affect arterioles, capillaries and small veins supplying the …

Vascular dementia (VaD) is a major contributor to the dementia syndrome and is described
as having problems with reasoning, planning, judgment, and memory caused by impaired …

SVD is the leading cause of VCI and is associated with substantial morbidity. Tackling
cardiovascular risk factors is currently the most effective approach to prevent cognitive …