Meta-analysis of cohort and case–control studies of type 2 diabetes mellitus and risk of atrial fibrillation

RR Huxley, KB Filion, S Konety, A Alonso - The American journal of …, 2011 - Elsevier
Atrial fibrillation (AF) is 1 of the most clinically diagnosed cardiac disturbances but little is
known about its risk factors. Previous epidemiologic studies have reported on the …

Arrhythmogenic substrates for atrial fibrillation in obesity

ER Lubbers, MV Price, PJ Mohler - Frontiers in physiology, 2018 - frontiersin.org
Global obesity rates have nearly tripled since 1975. This obesity rate increase is mirrored by
increases in atrial fibrillation (AF) that now impacts nearly 10% of Americans over the age of …

Disease–treatment interactions in the management of patients with obesity and diabetes who have atrial fibrillation: the potential mediating influence of epicardial …

M Packer - Cardiovascular diabetology, 2019 - Springer
Both obesity and type 2 diabetes are important risk factors for atrial fibrillation (AF), possibly
because they both cause an expansion of epicardial adipose tissue, which is the source of …

Are interactions between epicardial adipose tissue, cardiac fibroblasts and cardiac myocytes instrumental in atrial fibrosis and atrial fibrillation?

A Krishnan, E Chilton, J Raman, P Saxena… - Cells, 2021 - mdpi.com
Atrial fibrillation is very common among the elderly and/or obese. While myocardial fibrosis
is associated with atrial fibrillation, the exact mechanisms within atrial myocytes and …

Oxidative Stress, Inflammation, and Mitochondrial Dysfunction: A Link between Obesity and Atrial Fibrillation

AI Balan, VB Halațiu, A Scridon - Antioxidants, 2024 - mdpi.com
The adipose tissue has long been thought to represent a passive source of triglycerides and
fatty acids. However, extensive data have demonstrated that the adipose tissue is also a …

Atrial fibrillation and diabetes mellitus: can we modify stroke risk through glycemic control?

FE Ugowe, LR Jackson, KL Thomas - Circulation: Arrhythmia and …, 2019 - Am Heart Assoc
(95% CI, 1.54–3.70) for patients with HbA1c of 49 to 58 mmol/mol and 2.58 (95% CI, 1.56–
4.29) for patients with HbA1c> 58 mmol/mol. 8 Interestingly, when the duration of diabetes …

Autonomic dysfunction is associated with brief episodes of atrial fibrillation in type 2 diabetes

MR Rizzo, FC Sasso, R Marfella, M Siniscalchi… - Journal of Diabetes and …, 2015 - Elsevier
Abstract Background and Aims This study aimed to investigate the relationship between
asymptomatic episodes of atrial fibrillation (AF) and abnormalities of the autonomic nervous …

Potential atrial arrhythmogenicity of adipocytes: implications for the genesis of atrial fibrillation

YK Lin, YJ Chen, SA Chen - Medical hypotheses, 2010 - Elsevier
Atrial fibrillation is the most common sustained cardiac arrhythmia. Obesity and metabolic
syndrome are independent risk factors for atrial fibrillation, and epicardial adipose tissues …

Atrial fibrillation is associated with impaired atrial mitochondrial energetics and supercomplex formation in adults with type 2 diabetes

GN Kanaan, DA Patten, CJ Redpath… - Canadian Journal of …, 2019 - Elsevier
Objectives Type 2 diabetes mellitus is a chronic progressive disease that is associated with
increased risk for cardiovascular diseases and with impaired mitochondrial metabolism in …

Diabetes influences the cardiac symptoms related to atrial fibrillation

K Sugishita, E Shiono, T Sugiyama, T Ashida - Circulation journal, 2003 - jstage.jst.go.jp
It is well known that diabetes mellitus (DM) masks the cardiac symptoms during an ischemic
heart attack, but there have not been reports of whether DM influences the subjective …