[HTML][HTML] Transposable elements in human cancer: causes and consequences of deregulation
Transposable elements (TEs) comprise nearly half of the human genome and play an
essential role in the maintenance of genomic stability, chromosomal architecture, and …
essential role in the maintenance of genomic stability, chromosomal architecture, and …
Human population-specific gene expression and transcriptional network modification with polymorphic transposable elements
Transposable element (TE) derived sequences are known to contribute to the regulation of
the human genome. The majority of known TE-derived regulatory sequences correspond to …
the human genome. The majority of known TE-derived regulatory sequences correspond to …
RNAs from all categories generate retrosequences that may be exapted as novel genes or regulatory elements
J Brosius - Gene, 1999 - Elsevier
While the significance of middle repetitive elements had been neglected for a long time,
there are again tendencies to ascribe most members of a given middle repetitive sequence …
there are again tendencies to ascribe most members of a given middle repetitive sequence …
Transposable elements donate lineage-specific regulatory sequences to host genomes
L Marino-Ramirez, KC Lewis, D Landsman… - … and genome research, 2005 - karger.com
The evolutionary implications of transposable element (TE) influences on gene regulation
are explored here. An historical perspective is presented to underscore the importance of TE …
are explored here. An historical perspective is presented to underscore the importance of TE …
[HTML][HTML] Mammalian-wide interspersed repeat (MIR)-derived enhancers and the regulation of human gene expression
Background Mammalian-wide interspersed repeats (MIRs) are the most ancient family of
transposable elements (TEs) in the human genome. The deep conservation of MIRs initially …
transposable elements (TEs) in the human genome. The deep conservation of MIRs initially …
Exaptation of Transposable Elements into Novel Cis-Regulatory Elements: Is the Evidence Always Strong?
FSJ de Souza, LF Franchini… - Molecular biology and …, 2013 - academic.oup.com
Transposable elements (TEs) are mobile genetic sequences that can jump around the
genome from one location to another, behaving as genomic parasites. TEs have been …
genome from one location to another, behaving as genomic parasites. TEs have been …
The impact of transposable elements on mammalian development
JL Garcia-Perez, TJ Widmann, IR Adams - Development, 2016 - journals.biologists.com
Despite often being classified as selfish or junk DNA, transposable elements (TEs) are a
group of abundant genetic sequences that have a significant impact on mammalian …
group of abundant genetic sequences that have a significant impact on mammalian …
The 3′ ends of tRNA-derived short interspersed repetitive elements are derived from the 3′ ends of long interspersed repetitive elements
Short interspersed repetitive elements (SINEs) are a type of retroposon, being members of a
class of informational molecules that are amplified via cDNA intermediates and flow back …
class of informational molecules that are amplified via cDNA intermediates and flow back …
Widespread contribution of transposable elements to the innovation of gene regulatory networks
Transposable elements (TEs) have been shown to contain functional binding sites for
certain transcription factors (TFs). However, the extent to which TEs contribute to the …
certain transcription factors (TFs). However, the extent to which TEs contribute to the …
Transposable elements as genetic regulatory substrates in early development
WD Gifford, SL Pfaff, TS Macfarlan - Trends in cell biology, 2013 - cell.com
The abundance and ancient origins of transposable elements (TEs) in eukaryotic genomes
has spawned research into the potential symbiotic relationship between these elements and …
has spawned research into the potential symbiotic relationship between these elements and …