Recent focus on the neonatal intestinal microbiome has advanced our knowledge of the
complex interplay between the intestinal barrier, the developing immune system, and …

Highlights•Identification of the main factors that affect the infant skin microbiome.•How infant
skin microbiome profiles are impacted by external factors and disease.•Knowledge gaps for …

As human skin hosts a diverse microbiota in health and disease, there is an emerging
consensus that dysregulated interactions between host and microbiome may contribute to …

The human integument and gastrointestinal tract host unique microbial ecosystems. Within
the last decade, research has focused on understanding the contributions of the microbiota …

Background Neonatal sepsis in preterm infants is often due to organisms that colonize the
skin including Staphylococcus spp. and Candida spp. Development and maturation of the …

Within days after birth, rapid surface colonization of infant skin coincides with significant
functional changes. Gradual maturation of skin function, structure, and composition …

The skin of preterm infants is a delicate organ with critical structural and functional
differences as compared to term born infants. Unique features contribute to an increased …

Early life is a dynamic period for skin microbial colonization and immune development. We
postulate that microbial exposures in this period durably alter the skin immune trajectory and …

Background The infant skin microbiota may serve as a reservoir of bacteria that contribute to
neonatal infections and stimulate local and systemic immune development. The objectives …

Daily practices put humans in close contact with the surrounding environment, and
differences in these practices have an impact on human physiology, development, and …