Small molecule, peptide, and protein-based drugs have been developed over decades to
treat various diseases. The importance of gene therapy as an alternative to traditional drugs …

Background Cardiovascular disease remains a major health care challenge. The knowledge
about the underlying mechanisms of the respective vascular disease etiologies has greatly …

Noncoding RNAs have been shown to exert important physiological and pathophysiological
functions. Various studies suggest that modulating noncoding RNAs may provide a …

The discovery of the roles of RNA other than just as a messenger, such as a ribozyme, and
regulatory RNAs, such as microRNA and long noncoding RNAs, is fascinating. RNA is now …

Hypertension is a global health problem, affecting developing and developed countries
alike. Most patients with hypertension are undiagnosed, and most diagnosed patients are …

Antisense inhibition of hypertension: A new strategy for renin-angiotensin candidate genes.
There are several ways of experimentally studying the influence of candidate genes on …

Abstract Purpose of Review Atherosclerotic cardiovascular disease (ASCVD) is still the
leading cause of death worldwide. Despite excellent pharmacological approaches, clinical …

Hypertension is a diverse illness interlinked with cerebral, cardiovascular (CVS) and renal
abnormalities. Presently, the malady is being treated by focusing on Renin-angiotensin …

This review focuses on antisense oligonucleotides and small interfering ribonucleic acid
therapies approved or under development for the management of lipid disorders. Recent …

The era of RNA medicine has become a reality with the success of messenger RNA (mRNA)
vaccines against COVID-19 and the approval of several RNA interference (RNAi) agents in …