A review of the evolving landscape of inclusive research and improved clinical trial access

SV Mohan, J Freedman - Clinical Pharmacology & …, 2023 - Wiley Online Library
Current clinical research does not reflect the diversity of patient populations, despite
continued recommendations to increase enrollment of under‐represented racial and ethnic …

Enhancing diversity and inclusion in clinical trials

A Corneli, E Hanlen‐Rosado… - Clinical …, 2023 - Wiley Online Library
Women and people from most racial and ethnic groups in the United States have historically
been under‐represented in clinical trials of investigational medical products. Inadequate …

Community engagement and clinical trial diversity: Navigating barriers and co-designing solutions—A report from the “Health Equity through Diversity” seminar series

L Reopell, TS Nolan, DM Gray, A Williams… - PloS one, 2023 - journals.plos.org
Introduction In recent years, there has been increasing awareness of the lack of diversity
among clinical trial participants. Equitable representation is key when testing novel …

[HTML][HTML] Diversity, equity, and inclusion in clinical trials: A practical guide from the perspective of a trial sponsor

S Versavel, A Subasinghe, K Johnson… - Contemporary Clinical …, 2023 - Elsevier
Background Considering diversity, equity, and inclusion (DEI) in clinical trials ensures that
data collected for investigational treatments reflect the populations most likely to benefit from …

Inclusion and diversity in clinical trials: actionable steps to drive lasting change

MD Kelsey, B Patrick-Lake, R Abdulai… - Contemporary Clinical …, 2022 - Elsevier
Background Improving diversity in clinical trials is essential in order to produce
generalizable results. Although the importance of representation has become increasingly …

Considerations for embedding inclusive research principles in the design and execution of clinical trials

U Peters, B Turner, D Alvarez, M Murray… - … Innovation & Regulatory …, 2023 - Springer
There is a growing recognition that the clinical research enterprise has a diversity problem,
given that many clinical trials recruit historically marginalized individuals or patients …

Opportunities to Increase Science of Diversity and Inclusion in Clinical Trials: Equity and a Lack of a Control

JK Igwe, TY Wangdak Yuthok, E Cruz… - Journal of the …, 2023 - Am Heart Assoc
The United States witnessed a nearly 4‐fold increase in personal health care expenditures
between 1980 and 2010. Despite innovations and obvious benefits to health, participants …

[HTML][HTML] Advancing inclusive research: establishing collaborative strategies to improve diversity in clinical trials

O Garrick, R Mesa, A Ferris, ES Kim, E Mitchell… - Ethnicity & …, 2022 - ncbi.nlm.nih.gov
Well-characterized disparities in clinical research have disproportionately affected patients
of color, particularly in underserved communities. To tackle these barriers, Genentech …

Promoting clinical trial diversity: a highlight of select US FDA initiatives

A Ramamoorthy, R Araojo, KP Vasisht… - Clinical …, 2023 - Wiley Online Library
Although the population in the United States is diverse, there are disparities in healthcare
outcomes in some populations, for example, based on characteristics such as race, ethnicity …

[PDF][PDF] Achieving diversity, inclusion, and equity in clinical research

BE Bierer, SA White, LG Meloney… - … and Boston, MA: Multi …, 2020 - mrctcenter.org
Background• Clinical trials are needed to develop new treatments and new vaccines.•
Participants in trials should reflect the population affected by the disease, or those intended …