[HTML][HTML] Ferroptosis mechanisms and regulations in cardiovascular diseases in the past, present, and future

W Fang, S Xie, W Deng - Cell Biology and Toxicology, 2024 - Springer
Cardiovascular diseases (CVDs) are the main diseases that endanger human health, and
their risk factors contribute to high morbidity and a high rate of hospitalization. Cell death is …

[HTML][HTML] Ferroptosis: a novel therapeutic target for ischemia-reperfusion injury

Y Chen, H Fan, S Wang, G Tang, C Zhai… - Frontiers in Cell and …, 2021 - frontiersin.org
Ischemia-reperfusion (I/R) injury is a major cause of cell death and organ damage in
numerous pathologies, including myocardial infarction, stroke, and acute kidney injury …

[HTML][HTML] Targeting ferroptosis to treat cardiovascular diseases: a new continent to be explored

F Huang, R Yang, Z Xiao, Y Xie, X Lin, P Zhu… - Frontiers in Cell and …, 2021 - frontiersin.org
Cardiovascular diseases, including cardiomyopathy, myocardial infarction, myocardial
ischemia/reperfusion injury, heart failure, vascular injury, stroke, and arrhythmia, are …

[HTML][HTML] Emerging roles of ferroptosis in cardiovascular diseases

K Wang, XZ Chen, YH Wang, XL Cheng, Y Zhao… - Cell death …, 2022 - nature.com
The mechanism of cardiovascular diseases (CVDs) is complex and threatens human health.
Cardiomyocyte death is an important participant in the pathophysiological basis of CVDs …

[HTML][HTML] Ferroptosis and its role in cardiomyopathy

D Li, W Pi, Z Sun, X Liu, J Jiang - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Heart disease is the leading cause of death worldwide. Cardiomyopathy is a disease
characterized by the heart muscle damage, resulting heart in a structurally and functionally …

[HTML][HTML] The link between ferroptosis and cardiovascular diseases: a novel target for treatment

H Hu, Y Chen, L Jing, C Zhai, L Shen - Frontiers in Cardiovascular …, 2021 - frontiersin.org
Ferroptosis is an iron-dependent cell death, which is characterized by iron overload and
lipid peroxidation. Ferroptosis is distinct from apoptosis, necroptosis, autophagy, and other …

[HTML][HTML] Ferroptosis: a new strategy for cardiovascular disease

Y Wang, J Wu - Frontiers in Cardiovascular Medicine, 2023 - frontiersin.org
Cardiovascular disease (CVD) is currently one of the prevalent causes of human death. Iron
is one of the essential trace elements in the human body and a vital component of living …

Ferroptosis in myocardial infarction: not a marker but a maker

X Wang, S Kang - Open Biology, 2021 - royalsocietypublishing.org
Identification of effective cardiac biomarkers and therapeutic targets for myocardial infarction
(MI) will play an important role in early diagnosis and improving prognosis. Ferroptosis, a …

[HTML][HTML] The role of ferroptosis in adverse left ventricular remodeling following acute myocardial infarction

K Komai, NK Kawasaki, JK Higa, T Matsui - Cells, 2022 - mdpi.com
Ferroptosis is an iron-dependent form of regulated cell death and is distinct from other
conventional forms of regulated cell death. It is often characterized by the dysfunction of the …

Molecular mechanisms of ferroptosis in cardiovascular disease

Q Zeng, T Jiang - Molecular and Cellular Biochemistry, 2024 - Springer
Ferroptosis is a newly recognized type of regulated cell death that is characterized by the
accumulation of iron and lipid peroxides in cells. Studies have shown that ferroptosis plays a …