Cardiovascular diseases (CVDs) are still a major cause of global mortality and disability,
seriously affecting people's lives. Due to the severity and complexity of these diseases, it is …

Heart disease is the leading cause of death worldwide. A key pathogenic factor in the
development of lethal heart failure is loss of terminally differentiated cardiomyocytes …

Ischemia-reperfusion (I/R) injury is a major challenge in perioperative medicine that
contributes to pathological damage in various conditions, including ischemic stroke …

Iron is an essential mineral participating in different functions of the organism under
physiological conditions. Numerous biological processes, such as oxygen and lipid …

Diabetic cardiomyopathy (DC) is a serious heart disease caused by diabetes. It is unrelated
to hypertension and coronary artery disease and can lead to heart insufficiency, heart failure …

Iron overload increases the production of harmful reactive oxygen species in the Fenton
reaction, which causes oxidative stress in the body and lipid peroxidation in the cell …

Ferroptosis is classified as an iron-dependent form of regulated cell death (RCD) attributed
to the accumulation of lipid hydroperoxides and redox imbalance. In recent years …

Ferroptosis is a unique and pervasive form of regulated cell death driven by iron-dependent
phospholipid peroxidation. It results from disturbed cellular metabolism and imbalanced …

Abstract Background Ischemia/reperfusion (I/R) is associated with severe cellular damage
and death. Ferroptosis, a new form of regulated cell death caused by the accumulation of …

Ferroptosis is a new type of cell death that was discovered in recent years and is usually
accompanied by a large amount of iron accumulation and lipid peroxidation during the cell …