Gene therapy for hypertension: antisense inhibition with adeno-associated viral vector delivery targeting angiotensin II type 1 receptor messenger ribonucleic acid
MI Phillips - American Journal of Cardiology, 1998 - ajconline.org
The goal of gene therapy for hypertension is to provide treatment that decreases blood
pressure for much longer than can be achieved using a single dose of currently available …
pressure for much longer than can be achieved using a single dose of currently available …
Gene therapy to control hypertension: current studies and future perspectives
MA Moore, KW Sellers, CH Gelband… - The American journal of …, 2001 - Elsevier
Hypertension is a complex pathophysiological state that leads to serious complications,
including heart failure, coronary artery disease, and abnormal renal function. While …
including heart failure, coronary artery disease, and abnormal renal function. While …
Targeting of the renin-angiotensin system by antisense gene therapy: a possible strategy for the long-term control of hypertension
MK Raizada, SC Francis, H Wang… - Journal of …, 2000 - journals.lww.com
Traditional pharmacological agents have been successfully used for the treatment of
hypertension for a number of decades. However, this therapeutic regimen has reached a …
hypertension for a number of decades. However, this therapeutic regimen has reached a …
Gene therapy for hypertension: antisense inhibition of the renin-angiotensin system
MI Phillips, B Kimura - Hypertension: Methods and Protocols, 2005 - Springer
Despite excellent antihypertensive drugs on the market, about 70% of all hypertensive
patients do not have their blood pressure under control. This is due to problems of …
patients do not have their blood pressure under control. This is due to problems of …
Gene therapy for hypertension: A review of potential targets
J Chao, C Wang, L Chao - Biodrugs, 1999 - Springer
Somatic gene delivery approaches have received wide attention as a new technique for
studying gene expression and as a potential therapeutic tool in treating both inherited and …
studying gene expression and as a potential therapeutic tool in treating both inherited and …
Gene therapy for hypertension: sense and antisense strategies
MI Phillips - Expert Opinion on Biological Therapy, 2001 - Taylor & Francis
Gene therapy for hypertension is needed for the next generation of antihypertensive drugs.
Current drugs, although effective, have poor compliance, are expensive and short-lasting …
Current drugs, although effective, have poor compliance, are expensive and short-lasting …
Gene therapy for hypertension: the preclinical data
MI Phillips - Hypertension, 2001 - Am Heart Assoc
Despite several drugs for the treatment of hypertension, there are many patients with poorly
controlled high blood pressure. This is partly because all of the available drugs are short …
controlled high blood pressure. This is partly because all of the available drugs are short …
Is antisense gene therapy a step in the right direction in the control of hypertension?
MK Raizada, MJ Katovich, H Wang… - American Journal …, 1999 - journals.physiology.org
HYPERTENSION is a complex pathophysiological state primarily expressed as chronic high
blood pressure (BP). If unchecked and uncontrolled, it affects major vital organs, including …
blood pressure (BP). If unchecked and uncontrolled, it affects major vital organs, including …
Gene-Based Therapy for Hypertension–Do Preclinical Data Suggest a Promising Future?
GM Puddu, E Cravero, E Ferrari, A Muscari, P Puddu - Cardiology, 2007 - karger.com
Many experimental studies have obtained a prolonged control of blood pressure through
gene treatment. This consists in the administration of genes coding for vasodilator proteins …
gene treatment. This consists in the administration of genes coding for vasodilator proteins …
The future of hypertension therapy: sense, antisense, or nonsense?
AS Pachori, MJ Huentelman, SC Francis… - …, 2001 - Am Heart Assoc
Hypertension is a debilitating disease with significant socioeconomic and emotional impact.
Despite recent success in the development of traditional pharmacotherapy for the …
Despite recent success in the development of traditional pharmacotherapy for the …
相关搜索
- antisense inhibition gene therapy
- renin angiotensin gene therapy
- receptor messenger gene therapy
- vector delivery gene therapy
- vector delivery receptor messenger
- antisense inhibition receptor messenger
- vector delivery antisense inhibition
- control of hypertension gene therapy
- antisense inhibition renin angiotensin
- promising future therapy for hypertension
- right direction gene therapy
- renin angiotensin genetic targeting