The microbiome has an important role in human health. Changes in the microbiota can
confer resistance to or promote infection by pathogenic bacteria. Antibiotics have a profound …

Growing evidence indicates that the gut microbiota plays a significant role in the
pathophysiological processes of obesity and its related metabolic symptoms in the host …

Lack of reproducibility is a prominent problem in biomedical research. An important source
of variation in animal experiments is the microbiome, but little is known about specific …

Methods capable of maintaining gut microbiota homeostasis to prevent bacterial
translocation and infection under external threats are critical for multiple facets of human …

Commensal bacteria in the lower intestine of mammals are 10 times as numerous as the
body's cells. We investigated the relative importance of different immune mechanisms in …

The commensal microbiota has an important impact on host health, which is only beginning
to be elucidated. Despite the presence of fungal, archaeal, and viral members, most studies …

Metabolites from intestinal microbiota are key determinants of host-microbe mutualism and,
consequently, the health or disease of the intestinal tract. However, whether such host …

The constituents of the gut microbiome are determined by the local habitat, which itself is
shaped by immunological pressures, such as mucosal IgA. Using a mouse model of …

Genetics provides a potentially powerful approach to dissect host-gut microbiota
interactions. Toward this end, we profiled gut microbiota using 16s rRNA gene sequencing …

The dramatic increase in food allergy prevalence and severity globally requires effective
strategies. Food allergy derives from a defect in immune tolerance mechanisms. Immune …