Summary bNAbs may offer advantages over traditional ART for both the prevention and
treatment of HIV-1 infection. In addition, bNAbs may target the latent viral reservoir. bNAb …

Early clinical studies support additional evaluation of bNAbs. Antibodies may offer
advantages over standard ART for HIV-1 prevention and therapy, and as components of …

Encouraging results from preclinical and clinical studies support the development of bNAbs
for prevention and a number of antibodies with exceptional breadth and potency are …

Highlights•Broadly neutralizing antibodies are promising for HIV-1 prevention and
therapy.•Newly identified bNAbs reveal novel epitopes and binding modes.•Effective …

Broadly neutralizing antibodies (bNAbs) have been evaluated as promising agents in the
fight against infectious diseases. HIV-1-specific bNAbs, in particular, have been tested in …

Broadly neutralizing antibodies for treatment and prevention... : Current Opinion in HIV and
AIDS Broadly neutralizing antibodies for treatment and prevention of HIV-1 infection : Current …

Despite immense progress in our ability to prevent and treat HIV-1 infection, HIV-1 remains
an incurable disease and a highly efficacious HIV-1 vaccine is not yet available. Additional …

The design of next-generation bNAb-based combination or multispecific therapeutics for the
prevention and/or treatment of HIV-1 infection will need to leverage the complementarity of …

Antibodies that naturally develop in some individuals infected with human immunodeficiency
virus 1 (HIV-1) and are capable of broadly neutralizing diverse strains of HIV-1 are useful for …

Anti-HIV broadly neutralizing antibodies (bNAbs) offer a novel approach to treating,
preventing, or curing HIV. Pre-clinical models and clinical trials involving the passive transfer …