Objective: Inborn errors of immunity (IEI) are a heterogeneous group of disorders, affecting
different components of the immune system. Over 450 IEI related genes have been …

Inborn errors of immunity (IEI) are a heterogeneous group of monogenic disorders that
include primary immunodeficiency's and other disorders affecting different aspects of the …

Molecular diagnosis of inborn errors of immunity (IEI) poses critical implications for patient's
long-term prognosis, treatment options, and genetic counseling. Over the past decade, the …

Objective Inborn errors of immunity (IEI) are a heterogeneous group of disorders, affecting
different components of the immune system. Over 450 IEI related genes have been …

Primary immunodeficiency diseases refer to inborn errors of immunity (IEI) that affect the
normal development and function of the immune system. The phenotypical and genetic …

Patients with inborn errors of immunity (IEI) present with a heterogeneous clinical and
immunological phenotype, therefore a correct molecular diagnosis is crucial for the …

Purpose Owing to recent technological advancements, using next-generation sequencing
(NGS) and the accumulation of clinical experiences worldwide, more than 420 genes …

Inborn errors of immunity (IEIs) include several hundred gene defects affecting various
components of the immune system. As with other constitutional disorders, next-generation …

The advent of next-generation sequencing (NGS) technologies has greatly expanded our
understanding of both the clinical spectra and genetic landscape of inborn errors of …

Inborn errors of immunity (IEI), also known as primary immunodeficiency diseases, comprise
a group of rare genetic disorders that affect the development or/and function of the immune …