Antimicrobial, antiadhesive, and antibiofilm actions of rhamnolipids on ESKAPE pathogens

A Firdose, NHH Chong, R Ramli… - Letters in Applied …, 2023 - academic.oup.com
The aim of this study was to test the antimicrobial, antiadhesive, and antibiofilm activities of a
rhamnolipid extracted from Pseudomonas aeruginosa UKMP14T previously isolated from oil …

Elastase LasB of Pseudomonas aeruginosa promotes biofilm formation partly through rhamnolipid-mediated regulation

H Yu, X He, W Xie, J Xiong, H Sheng… - Canadian journal of …, 2014 - cdnsciencepub.com
Elastase LasB, an important extracellular virulence factor, is shown to play an important role
in the pathogenicity of Pseudomonas aeruginosa during host infection. However, the role of …

The rhamnolipid stress response of Bacillus subtilis

T Wecke, T Bauer, H Harth, U Mäder… - FEMS microbiology …, 2011 - academic.oup.com
Rhamnolipids are biosurfactants produced by the soil bacterium P seudomonas aeruginosa.
In addition to their high industrial potential as surface-active molecules, rhamnolipids also …

Anti-biofilm properties of bacterial di-rhamnolipids and their semi-synthetic amide derivatives

I Aleksic, M Petkovic, M Jovanovic… - Frontiers in …, 2017 - frontiersin.org
A new strain, namely Lysinibacillus sp. BV152. 1 was isolated from the rhizosphere of
ground ivy (Glechoma hederacea L.) producing metabolites with potent ability to inhibit …

[HTML][HTML] Interaction of rhamnolipids with model biomembranes of varying complexity

M Herzog, T Tiso, LM Blank, R Winter - Biochimica et Biophysica Acta (BBA …, 2020 - Elsevier
Rhamnolipids represent a large class of biologically produced surface-active compounds,
which participate in various essential cellular functions. While many studies have reported …

Distinct lipid a moieties contribute to pathogen-induced site-specific vascular inflammation

C Slocum, SR Coats, N Hua, C Kramer… - PLoS …, 2014 - journals.plos.org
Several successful pathogens have evolved mechanisms to evade host defense, resulting in
the establishment of persistent and chronic infections. One such pathogen, Porphyromonas …

Membrane lipid renovation in Pseudomonas aeruginosa ‐ implications for phage therapy?

R Lyon, RA Jones, H Shropshire… - Environmental …, 2022 - Wiley Online Library
Pseudomonas aeruginosa is an important Gram‐negative pathogen with intrinsic resistance
to many clinically used antibiotics. It is particularly troublesome in nosocomial infections …

Lipid A Has Significance for Optimal Growth of Coxiella burnetii in Macrophage-Like THP-1 Cells and to a Lesser Extent in Axenic Media and Non-phagocytic Cells

T Wang, Y Yu, X Liang, S Luo, Z He, Z Sun… - Frontiers in cellular …, 2018 - frontiersin.org
Lipid A is an essential basal component of lipopolysaccharide of most Gram-negative
bacteria. Inhibitors targeting LpxC, a conserved enzyme in lipid A biosynthesis, are antibiotic …

Endotoxin-like properties of a rhamnolipid exotoxin from Burkholderia (Pseudomonas) plantarii: immune cell stimulation and biophysical characterization

J Andrä, J Rademann, J Howe, MHJ Koch, H Heine… - 2006 - degruyter.com
Here we report on the purification, structural characterization, and biological activity of a
glycolipid, 2-O-α-L-rhamnopyranosyl-α-L-rhamnopyranosyl-α (R)-3-hydroxytetradecanoyl …

Pseudomonas aeruginosa N-3-oxo-dodecanoyl-homoserine Lactone Elicits Changes in Cell Volume, Morphology, and AQP9 Characteristics in Macrophages

A Holm, KE Magnusson, E Vikström - Frontiers in Cellular and …, 2016 - frontiersin.org
Quorum sensing (QS) communication allows Pseudomonas aeruginosa to collectively
control its population density and the production of biofilms and virulence factors. QS signal …