Rational design, synthesis, and structure− activity relationships of novel factor Xa inhibitors:(2-substituted-4-amidinophenyl) pyruvic and-propionic acids

K Sagi, T Nakagawa, M Yamanashi… - Journal of medicinal …, 2003 - ACS Publications
An inhibitor of factor Xa (fXa), the m-substituted benzamidine AXC1578 (1a), was structurally
modified with the aim of increasing its potency. In particular, pyruvic acid and propionic acid …

Rational design, synthesis, and structure-activity relationships of novel factor Xa inhibitors:(2-substituted-4-amidinophenyl) pyruvic and-propionic acids

K Sagi, T Nakagawa, M Yamanashi… - Journal of …, 2003 - pubmed.ncbi.nlm.nih.gov
An inhibitor of factor Xa (fXa), the m-substituted benzamidine AXC1578 (1a), was structurally
modified with the aim of increasing its potency. In particular, pyruvic acid and propionic acid …

Rational design, synthesis, and structure-activity relationships of novel factor Xa inhibitors:(2-substituted-4-amidinophenyl) pyruvic and-propionic acids.

K Sagi, T Nakagawa, M Yamanashi… - Journal of Medicinal …, 2003 - europepmc.org
An inhibitor of factor Xa (fXa), the m-substituted benzamidine AXC1578 (1a), was structurally
modified with the aim of increasing its potency. In particular, pyruvic acid and propionic acid …

[引用][C] Rational Design, Synthesis, and Structure− Activity Relationships of Novel Factor Xa Inhibitors:(2-Substituted-4-amidinophenyl) pyruvic and-propionic Acids 1

K Sagi, T Nakagawa, M Yamanashi, S Makino… - Journal of Medicinal …, 2003 - infona.pl
Rational Design, Synthesis, and Structure−Activity Relationships of Novel Factor Xa
Inhibitors: (2-Substituted-4-amidinophenyl)pyruvic and -propionic Acids 1 × Close The …

[引用][C] Rational design, synthesis, and structure-activity relationships of novel factor Xa inhibitors:(2-Substituted-4-amidinophenyl) pyruvic and-propionic acids

K SAGI, T NAKAGAWA, K ISHIKAWA… - Journal of medicinal …, 2003 - pascal-francis.inist.fr
Rational design, synthesis, and structure-activity relationships of novel factor Xa inhibitors: (2-Substituted-4-amidinophenyl)pyruvic
and -propionic acids CNRS Inist Pascal-Francis CNRS Pascal and Francis Bibliographic …

[引用][C] Rational design, synthesis, and structure-activity relationships of novel factor Xa inhibitors:(2-Substituted-4-amidinophenyl) pyruvic and-propionic acids

K SAGI, T NAKAGAWA… - Journal of …, 2003 - American Chemical Society