DNA methyltransferases: emerging targets for the discovery of inhibitors as potent anticancer drugs
J Yu, T Xie, Z Wang, X Wang, S Zeng, Y Kang… - Drug Discovery …, 2019 - Elsevier
Highlights•The structure-related regulatory mechanisms of active DNMTs are outlined.•The
therapeutic importance of DNMTs in different cancer types is briefly compared.•The most …
therapeutic importance of DNMTs in different cancer types is briefly compared.•The most …
DNA methyltransferases: emerging targets for the discovery of inhibitors as potent anticancer drugs
J Yu, T Xie, Z Wang, X Wang, S Zeng… - Drug discovery …, 2019 - pubmed.ncbi.nlm.nih.gov
DNA methyltransferases (DNMTs) are a conserved family of cytosine methylases with crucial
roles in epigenetic regulation. They have been considered as promising therapeutic targets …
roles in epigenetic regulation. They have been considered as promising therapeutic targets …
DNA methyltransferases: emerging targets for the discovery of inhibitors as potent anticancer drugs.
J Yu, T Xie, Z Wang, X Wang, S Zeng, Y Kang… - Drug Discovery …, 2019 - europepmc.org
DNA methyltransferases (DNMTs) are a conserved family of cytosine methylases with crucial
roles in epigenetic regulation. They have been considered as promising therapeutic targets …
roles in epigenetic regulation. They have been considered as promising therapeutic targets …