2, 4, 6-Triaminopyrimidine as a novel hinge binder in a series of PI3Kδ selective inhibitors

L Patel, J Chandrasekhar, J Evarts… - Journal of Medicinal …, 2016 - ACS Publications
Inhibition of phosphoinositide 3-kinase δ (PI3Kδ) is an appealing target for several
hematological malignancies and inflammatory diseases. Herein, we describe the discovery …

2, 4, 6-Triaminopyrimidine as a Novel Hinge Binder in a Series of PI3Kδ Selective Inhibitors

L Patel, J Chandrasekhar, J Evarts… - Journal of …, 2016 - pubmed.ncbi.nlm.nih.gov
Inhibition of phosphoinositide 3-kinase δ (PI3Kδ) is an appealing target for several
hematological malignancies and inflammatory diseases. Herein, we describe the discovery …

2, 4, 6-Triaminopyrimidine as a Novel Hinge Binder in a Series of PI3Kδ Selective Inhibitors.

L Patel, J Chandrasekhar, J Evarts… - Journal of Medicinal …, 2016 - europepmc.org
Inhibition of phosphoinositide 3-kinase δ (PI3Kδ) is an appealing target for several
hematological malignancies and inflammatory diseases. Herein, we describe the discovery …

[PDF][PDF] 2, 4, 6-Triaminopyrimidine as a Novel Hinge Binder in a Series of PI3Kδ Selective Inhibitors

L Patel, J Chandrasekhar, J Evarts, AC Haran, C Ip… - J. Med …, 2016 - researchgate.net
Inhibition of phosphoinositide 3-kinase δ (PI3Kδ) is an appealing target for several
hematological malignancies and inflammatory diseases. Herein, we describe the discovery …