[HTML][HTML] An engineered orco mutation produces aberrant social behavior and defective neural development in ants
H Yan, C Opachaloemphan, G Mancini, H Yang… - Cell, 2017 - cell.com
… orco mutations should significantly impact olfaction. We demonstrate striking functions of
Orco in odorant perception, reproductive physiology, and social behavior plasticity. Surprisingly…
Orco in odorant perception, reproductive physiology, and social behavior plasticity. Surprisingly…
[HTML][HTML] Orco mutagenesis causes loss of antennal lobe glomeruli and impaired social behavior in ants
W Trible, L Olivos-Cisneros, SK McKenzie, J Saragosti… - Cell, 2017 - cell.com
… in general olfactory behaviors. These ants also have deficiencies in social behavior, including
… insects, we also find that orco mutant ants possess striking neuro-anatomical phenotypes, …
… insects, we also find that orco mutant ants possess striking neuro-anatomical phenotypes, …
Neurodevelopmental and transcriptomic effects of CRISPR/Cas9-induced somatic orco mutation in honey bees
Z Chen, IM Traniello, S Rana… - Journal of …, 2021 - Taylor & Francis
… , an important model system for social behavior and chemical … After observing the antennal
lobe defects reported above, we … Such complicated evolution history makes it difficult to give a …
lobe defects reported above, we … Such complicated evolution history makes it difficult to give a …
Olfactory receptors are required for social behavior and neural plasticity in ants, as evidenced by CRISPR-mediated gene knockout
H Yan, C Opachaloemphan, G Mancini, H Yang… - BioRxiv, 2017 - biorxiv.org
… (leaving the colony to forage), most likely due to a defect in sensing … To address whether the
orco mutation affected dueling and the … This aberrant behavior is paradoxical given that the …
orco mutation affected dueling and the … This aberrant behavior is paradoxical given that the …
[HTML][HTML] Mutagenesis of the odorant receptor co-receptor (Orco) reveals severe olfactory defects in the crop pest moth Helicoverpa armigera
… Moreover, we examined the behaviors of their adults and larvae… inferred to produce a
nonfunctional, truncated Orco protein … these Ors from cell body to neuronal dendrites in H. …
nonfunctional, truncated Orco protein … these Ors from cell body to neuronal dendrites in H. …
[HTML][HTML] New tools, new insights—probing social behaviour in ants
D Clyde - Nature Reviews Genetics, 2017 - nature.com
… lobes of the brain was dramatically reduced in orco mutant ants, as … orco mutants, which
points to a possible role for orco in … the diverse social systems within ant species, makes them …
points to a possible role for orco in … the diverse social systems within ant species, makes them …
Orco-dependent survival of odorant receptor neurons in ants
B Sieriebriennikov, KR Sieber, O Kolumba… - Science …, 2024 - science.org
… in antennal ORNs in adult orco mutant ants, we performed … as long as they additionally
produced a functional IR/Irco … mechanism underlying their defective neural development. …
produced a functional IR/Irco … mechanism underlying their defective neural development. …
[HTML][HTML] Disruption of the odorant coreceptor Orco impairs foraging and host finding behaviors in the New World screwworm fly
… Out of the ten selected G 0 putative founders, nine produced … to rescue functional defects
in Orco mutants of Drosophila, … -classical model insects, including social behavior in ants 34 , …
in Orco mutants of Drosophila, … -classical model insects, including social behavior in ants 34 , …
Mutagenesis of odorant coreceptor Orco fully disrupts foraging but not oviposition behaviors in the hawkmoth Manduca sexta
RA Fandino, A Haverkamp… - Proceedings of the …, 2019 - National Acad Sciences
… mutation 1, facilitating the identification of the KO allele. Individuals with the Orco KO allele
produced … of the MsexOrco mutation, we analyzed antennal and brain responses to the sex …
produced … of the MsexOrco mutation, we analyzed antennal and brain responses to the sex …
Mutagenesis of the orco odorant receptor co-receptor impairs olfactory function in the malaria vector Anopheles coluzzii
… -dependent pathways, we designed a simple two-choice behavioral bioassay to test the … is
required for neuronal physiology as well as a range of downstream olfactory-driven behaviors. …
required for neuronal physiology as well as a range of downstream olfactory-driven behaviors. …