… modified with 2′-O,4′-C-ethylene-bridged nucleic acids (ENA) have a binding affinity to
ssRNA similar to those modified with 2′,4′-BNA/LNA ( Figure 1 ). Moreover, ENA modified …

… containing 2′-O,4′-C-ethylene-bridged nucleic acid (ENA) … the 2′-O,4′-C-methylene-linkage
of bridged nucleic acids (… On the other hand, the guanine of a G:C base pair of dsDNA …

… An improved synthesis of 2′-O,4′-C-ethylene nucleic acid (ENA) and thermodynamic
studies of duplex formation containing the guanosine ENA unit. Nucleosides, Nucleotides …

… nucleotides (LNAs) and 2′-O,4′-C-ethylene-bridged nucleotides (… evaluated
thermodynamically and compared with those of CRNs. … ENA or CRN into the A-form DNA/RNA …

… containing LNA. (9) These results suggest that 6′-Me-ENA can be expected as highly potential
nucleic acids. … The duplex-forming ability of the 6′S-Me-ENA-modified oligonucleotides …

… duplex-forming ability with ssRNA and resistance against nuclease, we considered that 2′-O,4′-C-methyleneoxy-bridged
nucleic acid … 2′,4′-BNA/LNA or ENA. Moreover, Me-TaNA …

… reported the synthesis and properties of 6′R-Me-ENA (Base = T, … reported on 2′-O,4′-C-methyleneoxy-bridged
nucleic acid (Me-… spectroscopy of nucleic acid duplexes and triplexes. …

… RNA duplexes are made up of ribofuranose sugars having C3… nucleic acid structure as
we can see in the case of 2′-SCF 3 and 2′-OCF 3 modifications. Contrastingly, the bulky 2′-O…

… Among them, 2′-O,4′-C-methylene-bridged nucleic acid (2… for the synthesis of 6′S-methyl-2′-O,4′-C-ethylene-…
also proceeded with adenine and guanine nucleosides to afford the …

… For instance, 2′,4′-bridged nucleic acids, such as ENA [18… of 2′-N,4′-C-ethylene-bridged
nucleic acid (azaENA) [28]. … 2′-O,4′-C-Ethyleneoxy bridged nucleic acid (EoNA) is the …