Detecting essential proteins based on network topology, gene expression data, and gene ontology information

W Zhang, J Xu, Y Li, X Zou - IEEE/ACM transactions on …, 2016 - ieeexplore.ieee.org
identifying essential proteins by combining network topology, gene expression profiles, and
GO information. … , and CowEWC) in detecting essential proteins from two different yeast PPI …

Predicting essential proteins by integrating network topology, subcellular localization information, gene expression profile and go annotation data

W Zhang, J Xu, X Zou - IEEE/ACM transactions on …, 2019 - ieeexplore.ieee.org
… Taken together, our new proposed method TEGS perform well in identifying essential
proteins from PPI network, especially when the select top number is relative large. …

A novel essential protein identification method based on PPI networks and gene expression data

J Zhong, C Tang, W Peng, M Xie, Y Sun, Q Tang… - BMC …, 2021 - Springer
… methods for identifying essential proteins have better results by using biological information.
… characterize the probability of two proteins being in a cluster from a topology perspective (2) …

CEGSO: boosting essential proteins prediction by integrating protein complex, gene expression, gene ontology, subcellular localization and orthology information

W Zhang, X Xue, C Xie, Y Li, J Liu, H Chen… - Interdisciplinary Sciences …, 2021 - Springer
… method to detect key proteins by incorporating network structure with gene expression profile,
protein complexes, GO annotation data, subcellular localization information, and orthology …

Prediction and analysis of essential genes using the enrichments of gene ontology and KEGG pathways

L Chen, YH Zhang, SP Wang, YH Zhang, T Huang… - PloS one, 2017 - journals.plos.org
Identifying essential genes in a given organism is important … to predict essential genes based
on biological and topological … al. provided a gene expression programming-based (GEP) …

Network-based methods for predicting essential genes or proteins: a survey

X Li, W Li, M Zeng, R Zheng, M Li - Briefings in bioinformatics, 2020 - academic.oup.com
network topological and biological properties. In Dynamic … provide a more comprehensive
gene expression profile. More … Accordingly, identifying the domains that occur within proteins

Comparative analysis of gene ontology-based semantic similarity measurements for the application of identifying essential proteins

X Xue, W Zhang, A Fan - Plos one, 2023 - journals.plos.org
Detecting essential proteins based on network topology, gene expression data, and Gene
Ontology information. IEEE/ACM transactions on computational biology and bioinformatics,…

Random walk based method to identify essential proteins by integrating network topology and biological characteristics

X Lei, X Yang, H Fujita - Knowledge-Based Systems, 2019 - Elsevier
… methods which have been used for essential protein detection. However, it is still a big …
method applies network topology (ECC), gene expression data (PCC) and GO annotation data (…

A new method for identifying essential proteins based on network topology properties and protein complexes

C Qin, Y Sun, Y Dong - PloS one, 2016 - journals.plos.org
… In future studies, we will integrate additional information, such as domain information,
gene ontology and gene expression data, to predict essential proteins more effectively and …

Integrating network topology, gene expression data and GO annotation information for protein complex prediction

W Zhang, J Xu, Y Li, X Zou - Journal of bioinformatics and …, 2019 - World Scientific
protein complexes by constructing a rened PPI network based on integrating gene expression
data and GO ontology … Y, Zou X, Detecting essential proteins based on network topology, …