[HTML][HTML] Estimating risk of antidepressant withdrawal from a review of published data

MA Horowitz, A Framer, MP Hengartner, A Sørensen… - CNS drugs, 2023 - Springer
… of antidepressant withdrawal from the existing literature on the subject. From this review,
we develop a preliminary risk calculator to estimate the risk of withdrawal symptoms in a given …

Incidence and risk factors of antidepressant withdrawal symptoms: a meta-analysis and systematic review

MM Zhang, X Tan, YB Zheng, N Zeng, Z Li… - Molecular …, 2024 - nature.com
… Further, we estimated the incidence of AWSs in the discontinued and continued
treatment groups stratified by treatment duration among 6 RCTs, respectively. As shown in …

[HTML][HTML] A systematic review into the incidence, severity and duration of antidepressant withdrawal effects: Are guidelines evidence-based?

J Davies, J Read - Addictive behaviors, 2019 - Elsevier
… We recommend that UK and USA guidelines on antidepressant withdrawal be urgently …
duration of withdrawal in the studies reviewed, thus rendering our overall estimates conservative. …

Predicting relapse after antidepressant withdrawal–a systematic review

IM Berwian, H Walter, E Seifritz, QJM Huys - Psychological medicine, 2017 - cambridge.org
… First, they found that relapse risk was higher after discontinuing antidepressants with larger
effects on the serotonergic or noradrenergic system. Since most studies in this review used …

Withdrawal syndrome following discontinuation of 28 antidepressants: pharmacovigilance analysis of 31,688 reports from the WHO spontaneous reporting database

C Gastaldon, G Schoretsanitis, E Arzenton, E Raschi… - Drug Safety, 2022 - Springer
… We performed three analyses: first, the main disproportionality analysis estimating the
ROR and IC of antidepressant-related withdrawal syndrome as compared to all other drugs …

Incidence of antidepressant discontinuation symptoms: a systematic review and meta-analysis

J Henssler, Y Schmidt, U Schmidt, G Schwarzer… - The Lancet …, 2024 - thelancet.com
… Subtracting non-specific effects, we estimate the frequency of antidepressant discontinuation
symptoms to be in the range of approximately 15%, thus affecting about one in six to seven …

Antidepressant withdrawal–the tide is finally turning

MP Hengartner, J Davies, J Read - Epidemiology and psychiatric …, 2020 - cambridge.org
… years after their SSRI review, Fava and colleagues also published a systematic review on
… on pre-selected participants produced somewhat lower estimates than more representative …

How effective are antidepressants for depression over the long term? A critical review of relapse prevention trials and the issue of withdrawal confounding

MP Hengartner - Therapeutic advances in …, 2020 - journals.sagepub.com
The aim of this article is to discuss the validity of relapse prevention trials and the issue of
withdrawal confounding in these trials. Recommendations for long-term antidepressant

The safety, tolerability and risks associated with the use of newer generation antidepressant drugs: a critical review of the literature

AF Carvalho, MS Sharma, AR Brunoni… - Psychotherapy and …, 2016 - karger.com
… In addition, an estimate indicates that antidepressants were the most frequently … review
suggested that dependence and withdrawal symptoms associated with newer antidepressants

[HTML][HTML] The need for antidepressant withdrawal support services: recommendations from 708 patients

J Read, S Lewis, M Horowitz, J Moncrieff - Psychiatry Research, 2023 - Elsevier
review has even been able to ‘outline a preliminary rubric for determining the risk of
withdrawal symptoms for a particular patient, which may have relevance for determining tapering …