… TTR genetic testing in amyloid subtyping, we performed a retrospective review of patients
with biopsy-proven ATTR amyloidosis. … MS/MS with proteomics and genetic testing. LC–MS/MS …

… Early and correct identification of ATTRv amyloidosis plays a … Subsequently, subtyping of
amyloid fibril can be performed by … causing TTR destabilization and increase the risk of ATTR …

… In addition, the utility of these agents in identifying ATTR-CM before increases in wall … the
amyloidosis subtype (eg, AL or ATTR). In patients with confirmed ATTR amyloidosis, TTR gene …

… light chains and transthyretin amyloidosis (ATTR) caused by … targeted ATTR therapies
offer the potential to improve … between amyloid subtypes or other infiltrative cardiac disorders, …

… ATTR-CM exists as 1 of 2 subtypes, defined by the precursor … Myocardial deposition of amyloid
fibrils increases the … in suboptimal recognition and identification of ATTR-CM. Traditional, …

… Subtypes and Pathogenesis ATTR-CM is classified genetically by the TTR gene into wild-…
with tandem mass spectrometry analysis helps with a definitive diagnosis of ATTR-CM. …

… progression in ATTR-PN and to improve survival in ATTR-CA. … gold standard for the diagnosis
and subtyping of ATTR-CA has … and genetic testing is required to identify TTR mutations. …

… TTR have been shown to improve outcomes for patients with … ATTR-CM is increasingly being
recognized by the cardiology … of nuclear scintigraphy to identify the presence of ATTR-CM. It …

… in cardiac imaging and diagnostic strategies have improved … CTS may accompany other
amyloidosis subtypes, but it is … Therefore, we believe that ATTR cardiac amyloidosis will soon be …

… Transthyretin cardiac amyloidosis (ATTR-CA) is a systemic disorder resulting from the
extracellular deposition of amyloid fibrils of misfolded transthyretin protein in the heart. …