… open label sacubitril/valsartan (<10%) in patients developing symptomatic heart failure
during the conduct of our trial, adopting the more expansive outcome of total events would have …

… PARADISE-MI trial provides an additional perspective into understanding the effects of
sacubitril/valsartan … -ratio analysis of sacubitril/valsartan versus ramipril based on events that met …

… Trial to Determine Superiority in Reducing Heart Failure Events After Myocardial Infarction)
tested the effect of sacubitril/valsartan compared with ramipril on LV function and adverse …

… :1, after the index event to receive either sacubitril/valsartan (… treatment effect of
sacubitril/valsartan in the PARADISE MI trial … fraction of patients included in the PARADISE MI trial …

… of cardiovascular death or heart failure … the effects of sacubitril/valsartan compared to
ramipril for the time to first occurrence of: heart failure hospitalization or outpatient heart failure (…

… In the whole trial population sacubitril/valsartan did not reduce the composite primary …
incident heart failure compared to ramipril. Whether or not event rates and/or treatment effects vary …

… systolic dysfunction (LVSD) combined with either heart failure (… the treatment effect and safety
of sacubitril/valsartan in patients … failure Events after Myocardial Infarction) N=5661 patients …

… Of sacubitril–valsartan versus Enalapril on Effect on NT-proB-… number of events with
sacubitril–valsartan versus ramipril, … In the overall context of existing literature, the PARADISE-MI …

… (5 mg twice daily) for reducing heart failure events after … Here, we report the effect of
sacubitril/valsartan versus ramipril on … artery disease (CAD)-related events in the PARADISE-MI …

… of initiation of sacubitril/valsartan in PARADISE-MI based on … events were similar between
sacubitril/valsartan and ramipril … Sacubitril/valsartan has pharmacological effects that warrant …