Intracellular organelles in health and kidney disease

FS Amiri - Nephrologie & therapeutique, 2019 - Elsevier
… Endoplasmic reticulum stress-induced pathological diseases in kidney cause … kidney. Due
to the accumulation in the proximal tubule lysosomes, impaired function of these organelles

[HTML][HTML] Organelle stress and metabolic derangement in kidney disease

R Inagi - International Journal of Molecular Sciences, 2022 - mdpi.com
… has revealed novel pathophysiological mechanisms in kidney disease. In particular, proteomic
and … organelle stress, organelle crosstalk, and metabolic derangement in kidney disease. …

[HTML][HTML] Organelle crosstalk in the kidney

T Inoue, H Maekawa, R Inagi - Kidney international, 2019 - Elsevier
… of organelles in kidney diseases and the mechanisms underlying organelle communication
… The activation of Nrf2 protects tissues against inflammation by increasing intracellular

[HTML][HTML] Pathophysiological role of organelle stress/crosstalk in AKI-to-CKD transition

H Maekawa, R Inagi - Seminars in nephrology, 2019 - Elsevier
… , and their damage is related to several kidney diseases. Organelles launch the stress …
followed by decreased ATP production and intracellular lipid accumulation, and thereby induced …

Mitochondria damage and kidney disease

P Duann, PH Lin - Mitochondrial Dynamics in cardiovascular medicine, 2017 - Springer
… prevent renal diseases progression. Mitochondria is the cell’s energy-producing organelle
… homeostasis, and therefore a major source of intracellular oxidative stress [11]. In addition to …

Organelle stress and glycation in kidney disease

R Inagi - Glycoconjugate Journal, 2021 - Springer
… by high glucose or decline of kidney function, leading to … proteins induce intracellular organelle
dysfunction in the kidney, … of kidney disease, such as chronic kidney disease and diabetic …

[HTML][HTML] The role of mitochondria in acute kidney injury and chronic kidney disease and its therapeutic potential

X Zhang, E Agborbesong, X Li - International journal of molecular …, 2021 - mdpi.com
… Mitochondria are intracellular organelles that contain an inner and outer membrane, with an
… connects mitochondria to other cellular organelles, including the endoplasmatic reticulum (…

[HTML][HTML] Molecular interactions between reactive oxygen species and autophagy in kidney disease

GP Kaushal, K Chandrashekar, LA Juncos - International journal of …, 2019 - mdpi.com
… Autophagy is an evolutionarily conserved, dynamic process of degradation of intracellular
organelles and macromolecules by lysosomal hydrolases. The degraded components, …

[HTML][HTML] Cell death in the kidney

G Priante, L Gianesello, M Ceol, D Del Prete… - International journal of …, 2019 - mdpi.com
… of unprocessed intracellular content, including cellular organelles, which … renal disease has
been investigated primarily through the mechanism of tubular damages. In acute renal failure

Mitochondrial dysfunction and oxidative stress: Role in chronic kidney disease

A Srivastava, B Tomar, D Sharma, SK Rath - Life Sciences, 2023 - Elsevier
… Fibrosis is the accumulation of extracellular matrix (ECM) in the kidneys, a frequent occurrence
… The energy-producing organelles, mitochondria, meet the enormous kidney metabolism …