… Neurodevelopmental factors, particularly pathways related to nervous system development,
… cell models. A number of induced pluripotent stem cell (iPSC) lines from BP patient and …

… bipolar disorders and schizophrenia, patient-derived models … future modelling efforts of
neurodevelopmental disorders. Future … iPSC-based disease modelling studies in these disorders. …

… , including autism spectrum disorder (ASD), schizophrenia (SZ), and bipolar disorder (BD), …
A central challenge in disease modeling with iPSC technology is to generate region-specific …

… In the case of bipolar disorder, there are no animal models available to represent both the
… Patient iPSC-based disease modeling has in a short time already shed light on the cellular …

… to model disease. We then discuss existing hiPSC models of neurodevelopmental disorders.
… Some evidence indicates that bipolar disorder has developmental origins 60 , and some …

… bona fide iPSC cell line of a Chinese bipolar patient carrying … one bone fide iPSC cell lines
from a bipolar patient who is a … GAT) and from another bipolar patient who is a carrier of the …

… Understanding the sources of variability in iPSC models of neurodevelopmental disorders, …
A recent paper modeling bipolar disorder (BD) provides an illustrative example of how well-…

… Schizophrenia (SCZ) and mood disorders (ie, major depression (MD) and bipolar disorder
(… to iPSC-disease modeling of early neurodevelopmental perturbations [22] and of disease …

… (iPSC) offers an unsurpassed opportunity to model human … of neuropsychiatric disorders
such as bipolar disorder, iPSC … BP and other neurodevelopmental disorders. Obtaining samples …

… disorders, including autism spectrum disorders, schizophrenia and bipolar disorder, point to
a neurodevelopmental origin … of reports on modelling ASD and SCZ using 2D human iPSC-…