Unmet therapeutic goals and potential treatable traits in a population of patients with severe uncontrolled asthma in Spain. ENEAS study

LP de Llano, E Martínez-Moragón, VP Moral… - Respiratory …, 2019 - Elsevier
… of inhaled corticosteroid and long-acting β-agonist (IC/LABA) … In addition, a post-bronchodilator
spirometry was performed … ) association with the predicted variable in a univariate …

[HTML][HTML] Adverse events among COPD patients treated with long-acting anticholinergics and β2-agonists in an outpatient respiratory clinic

C Rodrigue, MF Beauchesne, F Savaria, A Forget… - Respiratory …, 2016 - Elsevier
… The recommended first choices in pharmacologic therapy for stable COPD according to
each category are as follows: short-acting bronchodilators are recommended for patients in …

A systematic review with meta-analysis of dual bronchodilation with LAMA/LABA for the treatment of stable COPD

L Calzetta, P Rogliani, MG Matera, M Cazzola - Chest, 2016 - Elsevier
… Overall forest plot meta-analysis of the impact of long-acting muscarinic antagonist/long-acting
β2-agonist combinations on trough FEV 1 and subgroup analysis performed on lower and …

Spanish COPD guidelines (GesEPOC) 2017. Pharmacological treatment of stable chronic obstructive pulmonary disease

M Miravitlles, JJ Soler-Cataluña, M Calle… - Archivos de …, 2017 - Elsevier
… section on pharmacological treatment of stable COPD in the new … treatment will consist of
long-acting bronchodilators (LABD). … population were patients with FEV 1 <50% predicted, who …

The effect on total mortality of adding inhaled corticosteroids to long-acting bronchodilators for COPD: a real practice analysis in Italy

M Di Martino, N Agabiti, S Cascini… - … of Chronic Obstructive …, 2016 - Taylor & Francis
… PS were derived from predicted probabilities of treatment … factors, proxies of COPD severity,
concomitant respiratory … management of stable chronic obstructive pulmonary disease: …

Preventing Clinically Important Deterioration of COPD with Addition of Umeclidinium to Inhaled Corticosteroid/Long-Acting β2-Agonist Therapy: An Integrated Post …

IP Naya, L Tombs, DA Lipson, C Compton - Advances in Therapy, 2018 - Springer
… ; a predicted post-bronchodilator forced expiratory volume in 1 s (FEV 1 ) of ≤ 70%; a FEV
1 /forced vital capacity ratio of < 0.70 at first visit; and a score of ≥ 2 on the modified Medical …

Personalized medicine for patients with COPD: where are we?

FME Franssen, P Alter, N Bar… - … obstructive pulmonary …, 2019 - Taylor & Francis
… to predict morbidity and mortality of individual patients based on … While management of
stable COPD became more … for long-term treatment, long-acting bronchodilators are preferred. …

Inhaled corticosteroids in COPD: trying to make a long story short

C Tantucci, L Pini - … of Chronic Obstructive Pulmonary Disease, 2020 - Taylor & Francis
long-acting bronchodilators for high-risk symptomatic COPD … In fact, in subgroups of stable
COPD patients with high … trial where COPD patients (mean FEV 1 50% predicted) were …

Eosinophilic Inflammation in Chronic Obstructive Pulmonary Disease: A Treatable Trait

BC Govindan, P Augustine - Pulmon, 2024 - journals.lww.com
… that blood eosinophil counts predict the magnitude of the … or LAMA-LABA combination in
patients with stable COPD disease. … treatment in combination with long-acting bronchodilators in …

Dual bronchodilation for the treatment of COPD: from bench to bedside

M Cazzola, C Page, P Rogliani… - British Journal of …, 2022 - Wiley Online Library
… many patients who are receiving long-acting bronchodilators … LABA/LAMA FDCs in the
treatment of stable COPD were more … the New Zealand PREDICT Cardiovascular Disease Cohort …