Pleiotropy of Progesterone Receptor Membrane Component 1 in Modulation of Cytochrome P450 Activity

IS Barata, J Rueff, M Kranendonk, F Esteves - Journal of xenobiotics, 2024 - mdpi.com
… in resistance to the EGFR inhibitor erlotinib by binding to EGFR and initiating crosstalk
between the Wnt/β-catenin and NF-κB … and EGFR was linked with NF-κB activity stimulation in a …

Mechanism of metastasis suppression by luteolin in breast cancer

MT Cook - Breast Cancer: Targets and Therapy, 2018 - Taylor & Francis
… factors AP-1 and NF-κB. Citation27 MMPs promote … The Wnt/β-catenin pathway plays a
crucial role in morphogenesis … The Notch and Wnt/β-catenin pathways crosstalk, specifically …

Mechanisms of chemotherapy resistance in triple-negative breast cancer—how we can rise to the challenge

M Nedeljković, A Damjanović - Cells, 2019 - mdpi.com
… of Wnt/β-catenin signaling pathway constituents. Multiple … NF-κB, reduced the activation of
this pathway in TNBC cells … heterogeneity and crosstalk between signaling pathways will likely …

The E-cadherin and N-cadherin switch in epithelial-to-mesenchymal transition: signaling, therapeutic implications, and challenges

CY Loh, JY Chai, TF Tang, WF Wong, G Sethi… - Cells, 2019 - mdpi.com
… revealed to activate c-Myc and NF-κB pathway to promote the metastatic capability of tumor
crosstalk between cadherins and the canonical Wnt/β-catenin pathway exist and are linked

6-Shogaol Suppresses the Progression of Liver Cancer via the Inactivation of Wnt/-Catenin Signaling by Regulating TLR4

Y Zhang, J Wang, Y Qu, Y Chen - The American Journal of Chinese …, 2021 - World Scientific
Progesterone receptor membrane component 1 leads to erlotinib resistance, initiating
crosstalk of Wnt/β-catenin and NF-κB pathways, in lung adenocarcinoma cells. Sci. Rep. …

[HTML][HTML] Aberrant Notch signaling in gliomas: A potential landscape of actionable converging targets for combination approach in therapies resistance

M D'Amico, F De Amicis - Cancer Drug Resistance, 2022 - ncbi.nlm.nih.gov
… inhibitors (eg, gefinitib and erlotinib) have not caused clinical … receptor 2 (HER2), as well
as nuclear factor kappa B (NF-κB)… factor 1 alpha (HIF-1α) [28] , thus obtaining direct crosstalk

The molecular mechanisms and therapeutic potential of EZH2 in breast cancer

S Adibfar, M Elveny, HS Kashikova, MV Mikhailova… - Life sciences, 2021 - Elsevier
… , which requires the Wnt/β-catenin signaling axis. EZH2 … breast cancer cells, EZH2
establishes a functional cross-talk … complex with two NF-κB pathway core components, RelA …

B-GOS alleviates olanzapine-induced lipid disturbances in mice by enriching Akkermansia and upregulation of PGRMC1-Wnt signaling

C Zeng, H Chen, T Cao, L Wang, S Jiao, C Lin… - Food and Chemical …, 2024 - Elsevier
… the classical Wnt signaling (Wnt/β-catenin pathway), which is … Interestingly, in the
erlotinib-resistant PC9/ER cell line, the … foundation for the crosstalk between antipsychotics and …

… the proliferation of estrogen receptor-expressing (ER+) human breast adenocarcinoma by modulating PI3K/AKT, p38/ERK MAPK and associated signaling pathways

MA Siraj, AT Jacobs, GT Tan - Chemico-biological interactions, 2022 - Elsevier
… The AB-dependent downregulation of NF-κB was … Notably, GSK-3 also participates in
WNT/β-catenin signaling, promoting … Highly complex regulatory crosstalk signaling between JNK …

Macrophages are a double-edged sword: molecular crosstalk between tumor-associated macrophages and cancer stem cells

S Luo, G Yang, P Ye, N Cao, X Chi, WH Yang, X Yan - Biomolecules, 2022 - mdpi.com
… of tumor cells by regulating the nuclear factor-κB (NF-κB), … In addition, inhibition of WNT/β-catenin-WISP1
signaling can … T-cell-mediated cytotoxicity to CSCs and reduce the resistance of …