Synthetic blood and blood products for combat casualty care and beyond
… bovine, porcine and marine worm hemoglobins. The native hemoglobins have been modified
by polymerization, PEGylation… by cerebral vasospasm following subarachnoid hemorrhage…
by polymerization, PEGylation… by cerebral vasospasm following subarachnoid hemorrhage…
Use of hemoglobin for delivering exogenous carbon monoxide in medicinal applications
K Taguchi, T Maruyama… - Current Medicinal …, 2020 - ingentaconnect.com
… SanguinateTM, which is a PEG-modified bovine carboxyHb … with cerebral ischemia after a
subarachnoid hemorrhage [93]. … cerebral blood flow was not improved, reginal cerebral blood …
subarachnoid hemorrhage [93]. … cerebral blood flow was not improved, reginal cerebral blood …
Where is the clinical breakthrough of heme oxygenase-1/carbon monoxide therapeutics?
… a pegylated bovine carboxyhemoglobin (Sanguinate) which is … carboxyhemoglobin levels
in swine during desflurane and … ) Improves Cerebral Blood Flow to Vulnerable Brain Regions …
in swine during desflurane and … ) Improves Cerebral Blood Flow to Vulnerable Brain Regions …
Application of Causal Inference Methods in the Analysis of Observational Neurosurgical Data: G-Formula and Marginal Structural Model
… aneurysmal subarachnoid hemorrhage. In patients with DCI, cerebral blood flow (CBF) tends
… demand of their brain tissue; therefore, to increase CBF, induced hypertension for 1–2 days …
… demand of their brain tissue; therefore, to increase CBF, induced hypertension for 1–2 days …
Blood, Blood Components, Plasma, and Plasma Products
K Sobolewski, S Radparvar, C Wong… - Side Effects of Drugs …, 2018 - Elsevier
… PEGylated bovine carboxyhemoglobin to 12 patients with subarachnoid hemorrhage at risk
of delayed cerebral … IVIG-mediated increases in inflammatory cytokines or cerebral arterial …
of delayed cerebral … IVIG-mediated increases in inflammatory cytokines or cerebral arterial …
[HTML][HTML] When blood transfusion is not an option owing to religious beliefs
EP Crowe, RA DeSimone - Annals of Blood, 2022 - aob.amegroups.org
… These risks are correlated with the degree of anemia with sharp increase in risk once the …
, or cross-linked, human- or bovine-sourced Hgb molecules that seek to overcome the renal …
, or cross-linked, human- or bovine-sourced Hgb molecules that seek to overcome the renal …
Carbon Monoxide-bound Hemoglobin Vesicles: Current Facts and Potential Medical Applications
K Taguchi, K Matsumoto, H Sakai… - … BASED BLOOD …, 2022 - World Scientific
… on humoral sensitization of SANGUINATE infusion in patients … bovine) improves cerebral
blood flow to vulnerable brain … ences with PEGylated carboxyhemoglobin bovine in anemic …
blood flow to vulnerable brain … ences with PEGylated carboxyhemoglobin bovine in anemic …
Recruitment of monocytes primed to express heme oxygenase-1 ameliorates pathological lung inflammation in cystic fibrosis
C Di Pietro, HH Öz, P Zhang, E Cheng… - … & Molecular Medicine, 2022 - nature.com
… , a polyethylene-glycol-modified (PEGylated) bovine hemoglobin-based CO carrier 24,…
PEGylated, which enhances the compound’s stability and prolongs its retention in the circulation…
PEGylated, which enhances the compound’s stability and prolongs its retention in the circulation…
Targeting the heme oxygenase 1/carbon monoxide pathway to resolve lung hyper-inflammation and restore a regulated immune response in cystic fibrosis
C Di Pietro, HH Öz, TS Murray… - Frontiers in …, 2020 - frontiersin.org
… as Sanguinate), a polyethylene-glycol-modified (PEGylated) form of bovine hemoglobin …
in patients with other diseases, such as subarachnoid hemorrhage (SAH) (NCT02323685). …
in patients with other diseases, such as subarachnoid hemorrhage (SAH) (NCT02323685). …
Carbon monoxide releasing molecule 401 (CORM-401) modulates phase I metabolism of xenobiotics
M Walter, W Stahl, P Brenneisen, AS Reichert… - Toxicology in Vitro, 2019 - Elsevier
… EROD activity was calculated as increase of relative fluorescence units (RFU) per min. For
… Activity was calculated as increase in relative fluorescence units per min. Control was set to …
… Activity was calculated as increase in relative fluorescence units per min. Control was set to …