… -wide association studies have led to … early onset of the disease and men with inherited
germline variants in DNA repair genes are particularly at risk for harbouring aggressive histology. …

… is intraductal pathology or if the family history is suspicious. … at the European Society for
Medical Oncology 2019 meeting … a higher risk of PCa and early-onset disease, as supported by …

… advanced, early-onset, and familial prostate cancer genetic … of 441 patients with known
pathology), respectively. Although the … Medical Research Council and the Cancer Association of …

… the association of a GPV with the biology of a given cancer, … of histological diagnosis of
several family members with, … have a positive family history of any cancer and family history of …

… While early onset, multiple tumors, and family cancer history … population and occur in those
with a positive family history. … In a study of 2160 patients, no significant associations were …

… cancers with one of them being diagnosed at age <50, and patients with a strong family history
be … For example, we observed significantly more mucinous and signet ring histology in the …

… analyses for early-onset prostate cancer (diagnosis before 65 … the association between birth
weight and prostate cancer risk … Diagnoses were confirmed by medical record and pathology …

… disease. In addition to the Gleason score, the five-tier 2014 International Society of Urological
Pathology … in African American men) or with a family history of PCa. In addition men with a …

… of an early onset of disease and for developing lethal prostate … pathology at the time of
prostatectomy, risk of 10-year … the association of genetic profiling with MRI/prostate biopsy result in …

… , African ancestry, family history of the disease, circulating … between benign and GG4 prostate
histology (Gleason Score = 8)… protective association we observe with prostate cancer risk is …