… disease is characterized by several clinical and histological … one case of pancreatic or prostate
cancer. Secondly, in order … -clinical parameters mainly family history, early onset disease …

… risk for prostate cancer stem from genome-wide association … are at an increased risk for
early onset disease [34]. Other … pathology, Grade Group 4 PCa or above, or a family history of …

… cancer was defined as initial diagnosis of disease at 55 … to compare the disease course,
histopathological features, and … The early onset of prostate cancer poses a unique challenge to …

… Participants with positive family history of EC had … number of EC positive FDRs and EC family
history of early onset. … effect of family history on abnormal esophageal pathology remained …

… early-onset aggressive prostate cancer (PrCa). The IMPACT study is evaluating targeted
PrCa screening using prostate… test; and 31% reported a family history of PrCa. No statistically …

… in families, as well as early onset (EO) of disease [1,2]. Men in … association of family history
of prostate cancer and advanced … Clinical and histopathological characteristics of familial …

… of patients with a strong family history of early-onset PCa [20]. … detect occult prostate cancer
in histopathologically negative … its association with prostate cancer diagnosis and prognosis. …

… This subset of PCs, termed “early onset PC,” has been identified as a clinically discrete
entity… of Medical Genetics and Genomics and Association for Molecular Pathology consensus …

… Although deaths resulting from heart disease, prostate cancer, … of the disease, 24 whereas
NFT pathology correlates more … in AD dementia and show associations with both Aβ and tau …

… ; however, the majority of EO-PCa initiates without a known predisposing germ-line
component despite the strong association between EO-PCa incidence and family history [2] . …