… , prostate cancer, colorectal cancer, and … , family history of TC, radiation exposure, lymphocytic
thyroiditis, and reduced iodine intake (5, 6). On the basis of the histological and the clinical …

… , or at least two who have developed early-onset PCa (<55 years). … Genome-wide association
studies have identified 100 … T1b Tumour incidental histological finding in more than 5% …

… and meta-analyses, positive associations have been observed for … grade (histological) and
stage (SEER disease extent and … We examined early-onset PCa because we hypothesized …

… with early-onset breast cancer, triple-negative breast cancer, … , including the American Society
of Breast Surgeons (ASBrS), … of ovarian cancer, pancreatic cancer, and/or prostate cancer. …

… at presentation, and more unfavorable histological features. … The underlying mechanism
behind the association between obesity … However, in the absence of a positive family history, a …

… confirmed through medical record and pathology report … lethal prostate cancer, we would
expect a positive association … Also, as data for several potential confounders (eg, family history) …

… Associations with clinical and psychological factors were … The early onset of BF and the high
degree of similarity of BF … no), PSA level at diagnosis, histopathological Gleason grade group…

… diagnosis or family history, but rather for aggressive disease. … needed to establish associations
between these mutations … , animal models of prostate pathology, predictive biomarkers, …

… criteria (early onset, personal or family history of cancer and … , gender, race, histology, tumor
124 focality, tumor size, WHO … due to inconclusive association with pNET predisposition. In …

… Large-scale genome-wide association (GWAS) studies have … at a younger age or with a
family history of prostate cancer. … with early onset and increased disease aggressiveness. …