… is a widely used antiarrhythmic drug that can cause the development of steatohepatitis as
well as liver fibrosis and cirrhosis. The molecular mechanisms of amiodarone-mediated liver …

… [11] The bioavailability may be influenced by age, liver disease, and interactions with other
drugs or substances that inhibit or induce cytochrome (CYP) 450, thus affecting efficacy. …

Background Spontaneous reports of acute liver injuries (ALI) in patients taking dronedarone
triggered an EMA alert in 2011. This study aimed to assess the risk of ALI for class III …

… Four patients (6.6%) were diagnosed as liver cirrhosis before commencing amiodarone.
Mean loading and maintenance doses of amiodarone were 237.0±106.1 mg and 158.7±49.8 mg…

… Dronedarone, a chemically modified derivative of amiodarone, also … Amiodarone can cause
pulmonary fibrosis, corneal … of amiodarone induced hepatotoxicity in the form of cirrhosis, …

… Symptomatic liver disease due to oral amiodarone, as described in the case here, is rather
… amiodarone. A decision to continue should be based on an individual risk-benefit ratio. …

… Chronic liver injury from amiodarone may lead to lesions of varying nature which may … and
cirrhosis of liver [12]. Ndesmethylamiodarone is the major active metabolite of amiodarone is …

… levels without signs of cirrhosis as in our patient … amiodarone. Case Description/Methods:
A 74-year-old woman with medical history of non-ischemic cardiomyopathy, VT on amiodarone …

… central antiarrhythmic agent, amiodarone’s significant toxicity … similar to that of alcohol-induced
liver disease.[6, 7] Although … secondary to the IV infusions of amiodarone.[9] Unlike the …

… Amiodarone induced hepatotoxicity is a relatively rare adverse reaction which may complicate
further into hepatic fibrosis and cirrhosis. Here we present a case of amiodarone induced …