Gender-specific therapeutic approach in arterial hypertension–Challenges ahead

M Tadic, C Cuspidi, G Grassi, B Ivanovic - Pharmacological research, 2019 - Elsevier
… Sex hormones also have essential role in vascular function and … of the left ventricle typical
for arterial hypertension ejection … during monotherapy with ACEI (captopril) between genders, …

Small animal models of heart failure

C Riehle, J Bauersachs - Cardiovascular research, 2019 - academic.oup.com
… -morbidities of arterial hypertension and ischaemic heart disease. … ) inhibitor captopril
improves contractile function and survival … Multiple common comorbidities produce left ventricular

Impact of sacubitril/valsartan compared with ramipril on cardiac structure and function after acute myocardial infarction: the PARADISE-MI echocardiographic substudy

AM Shah, B Claggett, N Prasad, G Li, M Volquez… - Circulation, 2022 - Am Heart Assoc
… A sample size of 488 patients was determined to be necessary … the protective effects of
captopril.Circulation. 1994; 89:68–75. … Effect of the direct renin inhibitor aliskiren on left ventricular

… activates the SIRT1-AMPK-PGC1α signaling pathway to improve mitochondrial and oxidative damage in rats with chronic heart failure caused by myocardial infarction

S Yu, H Qian, D Tian, M Yang, D Li, H Xu… - Frontiers in …, 2023 - frontiersin.org
… Therefore, captopril-intervened heart failure rats were set as the … muscle (at the maximum
left ventricular diameter). The … gradient necessary to maintain the structure and function of …

Carthamus Tinctorius L. extract attenuates cardiac remodeling in L-NAME-induced hypertensive rats by inhibiting the NADPH oxidase-mediated TGF-β1 and MMP-9 …

S Bunbupha, P Pakdeechote, P Maneesai… - Annals Of Anatomy …, 2019 - Elsevier
… of hypertensive rats with CT extract or captopril significantly decreased systolic blood
pressure, left ventricular (… Effects of CT extract and captopril on LV morphology in L-NAME-induced …

Alterations in Ventricular Structure: Role of Left Ventricular Remodeling and Reverse Remodeling in Heart Failure

L Adamo, DL Mann - Heart Failure: A Companion to Braunwald's …, 2019 - books.google.com
… were randomized to placebo or captopril after an acute myocardial … Effect of cardiac
resynchronization therapy on left ventricular … That is, we simply do not understand what the …

[HTML][HTML] The renin–angiotensin–aldosterone-system and right heart failure in congenital heart disease

S Andersen, A Andersen, JE Nielsen-Kudsk - IJC Heart & Vasculature, 2016 - Elsevier
… life saving in pulmonary arterial hypertension and associated … effects of RAAS inhibition in
acquired left heart failure with an … essential for evaluation of safety and efficacy of heart failure

Epigenetics, inflammation and metabolism in right heart failure associated with pulmonary hypertension

N Samson, R Paulin - Pulmonary circulation, 2017 - journals.sagepub.com
… with left ventricular failure (LVF). However, right and left ventricles have many differences at
the morphological … Here we review basic principles such as mechanisms accounting for right …

[HTML][HTML] Morphological and functional characteristics of animal models of myocardial fibrosis induced by pressure overload

Y Ding, Y Wang, Q Jia, X Wang, Y Lu… - … journal of hypertension, 2020 - hindawi.com
… fibrosis, significant increase in left ventricular parameters such as … the effects of
sympathoinhibitory drugs on hypertensive heart … of right heart failure, not pulmonary hypertension

Metabolic changes in spontaneously hypertensive rat hearts precede cardiac dysfunction and left ventricular hypertrophy

J Li, BA Kemp, NL Howell, J Massey… - … of the American Heart …, 2019 - Am Heart Assoc
… To achieve the best fit, it was necessary to place the initial guess for k4 much … hypertensive
left ventricular hypertrophy: visualization, quantification and the effect on mechanical function