[HTML][HTML] Peripheral adaptive immunity of the triple transgenic mouse model of Alzheimer's disease
I St-Amour, CR Bosoi, I Paré… - Journal of …, 2019 - Springer
… triple transgenic mouse model (3xTg-AD) to reproduce Aβ (… Lymphocyte proportions were
not changed in the primary and … We also reported evidence of increased B and T lymphocyte …
not changed in the primary and … We also reported evidence of increased B and T lymphocyte …
[HTML][HTML] Translational modeling of psychomotor function in normal and AD-pathological aging with special concerns on the effects of social isolation
L Castillo-Mariqueo, L Giménez-Llort - Frontiers in Aging, 2021 - frontiersin.org
… the 3xTg-AD/ISO mice subgroup (n = 7) had a high motor … In particular, the grip has been
described as an alteration of … of places, 3xTg-AD mice exhibit these behaviors, which delays the …
described as an alteration of … of places, 3xTg-AD mice exhibit these behaviors, which delays the …
[HTML][HTML] Inflammation, neurodegeneration and protein aggregation in the retina as ocular biomarkers for Alzheimer's disease in the 3xTg-AD mouse model
A Grimaldi, C Brighi, G Peruzzi, D Ragozzino… - Cell Death & …, 2018 - nature.com
… In addition to cognitive and behavioral deficits, sensorial … Recent findings also demonstrated
the alteration in the level … analyzed Aβ accumulation in retinal samples from 3xTg-AD mice …
the alteration in the level … analyzed Aβ accumulation in retinal samples from 3xTg-AD mice …
[图书][B] Chronic Traffic Noise Exposure Contributes to Emergence of Cognitive and Motor Functions Impairment and Increases Amyloid-β Deposition in Mouse Model of …
H Karem - 2019 - search.proquest.com
… soluble fragment and insoluble plaque forms of Aβ exhibited … of stress on CORT hormone,
behavioral deficits, and Aβ … pre-stress and significantly increased in stress group compare to …
behavioral deficits, and Aβ … pre-stress and significantly increased in stress group compare to …
M344 promotes nonamyloidogenic amyloid precursor protein processing while normalizing Alzheimer's disease genes and improving memory
CH Volmar, H Salah-Uddin… - Proceedings of the …, 2017 - National Acad Sciences
… also show that M344 improves memory in the 3xTg AD mouse … , we hypothesized that Aβ
level would decrease in the … of learning and memory in different behavioral tests, with no effects …
level would decrease in the … of learning and memory in different behavioral tests, with no effects …
High fat diet treatment impairs hippocampal long-term potentiation without alterations of the core neuropathological features of Alzheimer disease
… in obese mice affected the results from the behavioral tasks, we … First, we evaluated the
effect of the diet on soluble Aβ … in social preference, high fat diet exposure did not alter social …
effect of the diet on soluble Aβ … in social preference, high fat diet exposure did not alter social …
Cognitive-enhancing effects of a polyphenols-rich extract from fruits without changes in neuropathology in an animal model of Alzheimer's disease
… in Aβ levels between male and female 3xTg-AD mice observed in … 3xTg-AD [72] and in
APP/PS1 mice [73], without altering Aβ or tau pathologies. Therefore, the PEBG-induced increase …
APP/PS1 mice [73], without altering Aβ or tau pathologies. Therefore, the PEBG-induced increase …
Behavioral and psychological symptoms of dementia (BPSD) and impaired cognition reflect unsuccessful neuronal compensation in the pre-plaque stage and serve …
A Pfeffer, T Munder, S Schreyer, C Klein… - Behavioural brain …, 2018 - Elsevier
… To minimize stress and avoid conflict or aggression in larger … Thus, in contrast to altered
anxiety-behavior, increased … reduced in a later disease stage of the 3xTg-AD model [100]. …
anxiety-behavior, increased … reduced in a later disease stage of the 3xTg-AD model [100]. …
[HTML][HTML] Glucocorticoids, synaptic plasticity and Alzheimer's disease
I Klyubin, T Ondrejcak, NW Hu, MJ Rowan - Current Opinion in Endocrine …, 2022 - Elsevier
… that excessive stress levels of glucocorticoids, acting via Aβ-, … PS1, APP, and tau genes
(3xTg-AD), mifepristone improved … Altered stress hormone levels affect in vivo vascular function …
(3xTg-AD), mifepristone improved … Altered stress hormone levels affect in vivo vascular function …
Stress and Alzheimer's disease: A senescence link?
CE Lyons, A Bartolomucci - Neuroscience & biobehavioral reviews, 2020 - Elsevier
… or chronic stress can cause changes in the brain and behavior in … the 3xTg-AD model, but
not the APP mutation, did not alter levels … The theory posits that an increase in Aβ 42 results in …
not the APP mutation, did not alter levels … The theory posits that an increase in Aβ 42 results in …