… leukoderma on his hands and pigmentation on the back of … phenolic skin whitening tyrosinase
inhibitors from leukoderma-… -butanol (4PB), and 4-n-butylresorcinol (4BR) were purchased …

… Tyrosinase inhibitors are extremely useful for controlling … indicating that tyrosinase inhibitors
can be effective chemical tools … for developing highly effective and safe tyrosinase inhibitors. …

… directly inhibit tyrosinase … inhibition of cAMP signaling and activation of p38 MAPK, indicating
that resorcinol may be a possible ameliorating agent in the treatment of hyperpigmentation …

… Melanogenesis and skin pigmentation are the most … (or resorcin)Citation 188 and 4-n-butylresorcinolCitation
189 , vanillin… 75% inhibition at 0.1 mM concentration and is highly effective …

… the most effective tyrosinase inhibitors. Skin pigmentation is also thought to be inhibited by
… as HQ 4% cream in the treatment of hyperpigmentation in darker skinned patients, with only …

… can efficiently prevent or correct UV- induced pigmentation. … , 2- MNG presented a very good
safety profile on nonexposed … . 4- n- butylresorcinol, a highly effective tyrosinase inhibitor for …

… on topical solutions recommended for hyperpigmentation. … improve hyperpigmentation
through its tyrosinase inhibition activity … The most effective interventions for their management are …

… or l-tyrosine.2, 6 In human skin, this pigmentation process … ) inhibited UVB-induced
hyperpigmentation most probably by … , 54, 102 The combination of 4-n-butylresorcinol (C 10 H 14 …

… Thus, it is evident that an effective and safe topical inhibitor of human … most effective approach
to reduce hyperpigmentation. However, the clinical efficacy of current tyrosinase inhibitors …

… a substrate in place of Ltyrosine. Furthermore, the presence of … ., Moraceae) leaf also inhibit
mushroom TYR. The compounds … ), and the positive control 4-n-butylresorcinol (50 and 83 µg/…