… ●Calcium channel disorders – A mutation in the gene that codes for the alpha-1 subunit of
… calcium channel in skeletal muscle is the most common genetic abnormality in hypokalemic …

… HypoPP is the most common cause of periodic paralysis. The four major differential …
Mutations linked to familial hypokalaemic periodic paralysis in the calcium channel alpha1 subunit …

… HypoPP-causing mutations in CACNA1S varies from asymptomatic to periodic paralysis with
… Most cases of HypoPP are caused by mutations in the calcium channel gene, CACNA1S. …

… -type α-1 subunit calcium channel of skeletal muscle; 20% have mutations in SCN4A gene
(… -gated sodium channel [3, 7]. In up to 3% of the HypoPP patients, the mutations have been …

… Background: Hypokalemic periodic paralysis (… causing recurrent episodes of flaccid
paralysis. Most cases are associated with CACNA1S mutation, causing defect of calcium channel …

… 1.4 channels expressed in Xenopus oocytes. Compared with Ca V 1.1, mutations of Na V 1.4
are a less frequent cause … of SCN4A mutations lagged the identification of calcium channel …

… -induced paralytic attacks. Our rare cases with typical hypokalaemic periodic paralysis …
the essential defect in hypokalaemic periodic paralysis mutant channels is the gating pore …

… the calcium channel defect can lead to episodes of weakness is not yet identified. In patients
with sodium channel defect, the paralysis … . Hypokalemic periodic paralysis with reversible …

… Ca v 1.1 α-subunit of dihydropyridine sensitive L-type voltage-gated calcium channel
Hypokalemic periodic paralysis … depolarization in hypokalemic periodic paralysis (HypoPP) which …

… hypokalemic periodic paralysis is related to mutations in the calcium channel gene CACNA1S
and the sodium channel … FHPP caused by calcium or sodium channel mutations. These …