CYP450 genotype and pharmacogenetic association studies: a critical appraisal
RR Shah, A Gaedigk, A LLerena… - …, 2016 - Future Medicine
… drug is well illustrated by perhexiline, an antianginal CYP2D6-… regard for concomitant
CYP2D6 inhibitor drugs may result in … Likewise, amiodarone which inhibits CYP2C9 is often co-…
CYP2D6 inhibitor drugs may result in … Likewise, amiodarone which inhibits CYP2C9 is often co-…
The importance of patient-specific factors for hepatic drug response and toxicity
VM Lauschke, M Ingelman-Sundberg - International Journal of Molecular …, 2016 - mdpi.com
… Furthermore, we highlight other parameters, such as concomitantly prescribed medications
… drugs are troglitazone, amiodarone, valproic acid and salicylate. While all of these drugs …
… drugs are troglitazone, amiodarone, valproic acid and salicylate. While all of these drugs …
Role of the surgical pathologist in diagnosis of drug-induced liver injury: recognizing specific patterns of drug injury
S Chopra, S Gawrieh, R Vuppalanchi… - Advances in Anatomic …, 2021 - journals.lww.com
… , 65 there was a case report each of bland … perhexiline maleate and 4,4′
diethylaminoethoxyhexestrol, 149,151 both of which are cationic amphiphilic drugs similar to …
diethylaminoethoxyhexestrol, 149,151 both of which are cationic amphiphilic drugs similar to …
[HTML][HTML] Mechanisms of anthracycline-induced cardiotoxicity: is mitochondrial dysfunction the answer?
A Murabito, E Hirsch, A Ghigo - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
… focused on preventing the disease concomitantly with ANT treatment, and secondary, when
… was found following perhexiline treatment compared to no change in patients treated with a …
… was found following perhexiline treatment compared to no change in patients treated with a …
Epidemiology of peripheral neuropathies
AF Haerer, DE Conwill, SH Subramony - Neuroepidemiology, 2019 - taylorfrancis.com
… identified and concomitant drugs were administered to every patient.44In another report of
11 … Perhexiline maleate, an antianginal drug, and amiodarone, an antiarrhythmic, are newer …
11 … Perhexiline maleate, an antianginal drug, and amiodarone, an antiarrhythmic, are newer …
Mitochondrial dysfunction induced by xenobiotics: Involvement in steatosis and steatohepatitis
K Begriche, J Massart, B Fromenty - Mitochondria in Obesity and Type 2 …, 2019 - Elsevier
… and the concomitant impairment of … amiodarone can induce steatosis and steatohepatitis.12,
25, 27 Investigations performed on isolated rodent mitochondria revealed that amiodarone …
25, 27 Investigations performed on isolated rodent mitochondria revealed that amiodarone …
Drug‐induced hepatotoxicity
D Larrey, J Ursic‐Bedoya… - Schiff's Diseases of the …, 2017 - Wiley Online Library
… have been viable without the concomitant development of a … Another case report outlined
cross-hepatotoxicity between … phospholipidosis, including perhexiline, amiodarone, and diethy…
cross-hepatotoxicity between … phospholipidosis, including perhexiline, amiodarone, and diethy…
[HTML][HTML] Diagnosis and management of secondary causes of steatohepatitis
R Liebe, I Esposito, HH Bock, S Vom Dahl, J Stindt… - Journal of …, 2021 - Elsevier
… and steatohepatitis development include amiodarone, diltiazem, … This class of drugs
comprises amiodarone, perhexiline, … A recent case series of 34 patients with anorexia nervosa …
comprises amiodarone, perhexiline, … A recent case series of 34 patients with anorexia nervosa …
[PDF][PDF] Investigation of Phenylacetylglycine and Hippuric Acid in Plasma as Potential Biomarkers for Drug-induced Phospholipidosis
上口英則 - 2018 - tsukuba.repo.nii.ac.jp
… monitored before and after treatment with amiodarone, a well… treated with chloroquine,
tamoxifen, quinacrine, perhexiline … CADs other than amiodarone and concomitant monitoring of …
tamoxifen, quinacrine, perhexiline … CADs other than amiodarone and concomitant monitoring of …
[HTML][HTML] Hepatotoxicity reports in the FDA adverse event reporting system database: A comparison of drugs that cause injury via mitochondrial or other mechanisms
… , and antimycobacterial drugs were the top five drug classes with the highest ROR values.
Although the top 20 drugs with the highest ROR values included drugs with both mitochondrial …
Although the top 20 drugs with the highest ROR values included drugs with both mitochondrial …