[HTML][HTML] Reliable subtype classification of diffuse large B-cell lymphoma samples from GELA LNH2003 trials using the Lymph2Cx gene expression assay

JP Jais, TJ Molina, P Ruminy, D Gentien, C Reyes… - …, 2017 - ncbi.nlm.nih.gov
… molecular subgroups originally defined according to gene … routine lab procedure as a
companion diagnostic test when … (LLMPP) described a digital gene expression-based assay using …

Leveraging gene expression subgroups to classify DLBCL patients and select for clinical benefit from a novel agent

A Risueño, PR Hagner, F Towfic… - Blood, The Journal …, 2020 - ashpublications.org
… de novo DLBCL patients, yielding 2 biologically distinct subgroupsDiffuse large B-cell
lymphoma (DLBCL) is a clinically and … Several gene expressionbased assays have been …

[HTML][HTML] … of immune-associated long non-coding RNA biomarkers associated with clinically molecular subtype and prognosis in diffuse large B cell lymphoma

M Zhou, H Zhao, W Xu, S Bao, L Cheng, J Sun - Molecular cancer, 2017 - Springer
gene predictor to diagnose clinical distinct subtype of DLBCL [3]. Cai et al. built an
expression-based signature incorporating up to 35 genes … into two distinctive patient subgroups

Double-hit gene expression signature defines a distinct subgroup of germinal center B-cell-like diffuse large B-cell lymphoma

D Ennishi, A Jiang, M Boyle, B Collinge… - Journal of Clinical …, 2019 - ascopubs.org
… from our previously described cohort of 347 diagnostic biopsy samples of patients with
de novo … The gene expressionbased model of 104 genes on the basis of high-grade B-cell …

[HTML][HTML] Improved personalized survival prediction of patients with diffuse large B-cell Lymphoma using gene expression profiling

A Mosquera Orgueira, JÁ Díaz Arias, M Cid López… - BMC cancer, 2020 - Springer
groups reported the identification of new DLBCL subgroups … biopsies of 420 patients
diagnosed with DLBCL according to … Kaplan-Meier plots of both 4-gene expression based clusters …

[HTML][HTML] Gene expression profiling-based risk prediction and profiles of immune infiltration in diffuse large B-cell lymphoma

S Merdan, K Subramanian, T Ayer… - Blood cancer …, 2021 - nature.com
… survival outcomes (alive or dead) at 2 and 5 years from diagnosis was also evaluated, … 1
was similar among these subgroups. The gene expression-based score was higher in ABC than …

[HTML][HTML] Cell-of-origin subtyping of diffuse large B-cell lymphoma by using a qPCR-based gene expression assay on formalin-fixed paraffin-embedded tissues

WH Yan, XN Jiang, WG Wang, YF Sun, YX Wo… - Frontiers in …, 2020 - frontiersin.org
… Using hierarchical clustering, there were at least two distinct groups within DLBCL: the …
The agreement between the gene expression-based assignments and the reference diagnoses

[HTML][HTML] Proposal and validation of a method to classify genetic subtypes of diffuse large B cell lymphoma

L Pedrosa, I Fernández-Miranda, D Pérez-Callejo… - Scientific reports, 2021 - nature.com
… We used targeted massive sequencing to analyze 84 diagnostic … generated three risk groups
with different clinical outcomes, as … of new genetic subtypes determined by distinct genetic

[HTML][HTML] Biological and clinical implications of gene-expression profiling in diffuse large B-cell lymphoma: a proposal for a targeted BLYM-777 consortium panel as …

FA de Groot, RAL de Groen, A van den Berg… - Cancers, 2022 - mdpi.com
… approaches with proteomic methods and correlate these multi-… multilayered methodology
potentially enhances diagnostic … DLBCL subgroup characterized by the prevalence of a distinct

Artificial intelligence analysis of gene expression data predicted the prognosis of patients with diffuse large B-cell lymphoma

J Carreras, R Hamoudi… - … experimental and clinical …, 2020 - discovery.ucl.ac.uk
… Using a risk score formula, the 25 genes identified two groups of patients with different …
Several distinct clinicopathologic entities are now considered separate diagnostic categories: the …